STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
engAGTP-binding protein, EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (469 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase, Cmk; Catalyzes the transfer of a phosphate group from ATP to either CMP or ump to form CDP or UDP and ADP [catalytic activity: ATP + CMP = ADP + CDP].
  
 0.999
MMAR_2526
Pseudouridylate synthase; Possible role in ribosome biogenesis and protein translation; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.989
MMAR_2525
Transcriptional regulator; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
 
  
 0.951
dnaG
DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.894
MMAR_2524
Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
  
 0.889
gpdA2
Glycerol-3-phosphate dehydrogenase [NAD(P)+] GpdA2; Involved in de novo phospholipid biosynthesis; glycerol-3 phosphate formation [catalytic activity: SN- glycerol 3-phosphate + NAD(P)(+) = glycerone phosphate + NAD(P)H]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.879
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
 
   
 0.838
gpdA1
Glycerol-3-phosphate dehydrogenase, GpdA1; Involved in de novo phospholipid biosynthesis; glycerol-3 phosphate formation [catalytic activity: SN- glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.833
MMAR_2523
ATPase involved in chromosome partitioning (Soj family); Function unknown, possible role in chromosome partioning.
       0.814
gmk
Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP.
 
  
 0.797
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.