STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lldD2L-lactate dehydrogenase (cytochrome) LldD2; Involved in respiration; catalyzes conversion of lactate into pyruvate [catalytic activity: (S)-lactate + 2 ferricytochrome C = pyruvate + 2 ferrocytochrome C]. (414 aa)    
Predicted Functional Partners:
MMAR_3408
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Function unknown; probably involved in cellular metabolism.
  
 
 0.956
lldD1
L-lactate dehydrogenase (cytochrome) LldD1; Involved in respiration; catalyzes conversion of lactate into pyruvate [catalytic activity: (S)-lactate + 2 ferricytochrome C = pyruvate + 2 ferrocytochrome C].
  
  
0.934
pykA
Pyruvate kinase PykA; Produces phosphoenol pyruvate in glycolysis [catalytic activity : ATP + pyruvate = ADP + phosphoenolpyruvate]; Belongs to the pyruvate kinase family.
  
 0.933
lldD1_1
L-lactate dehydrogenase (cytochrome) LldD1_1; Involved in respiration; catalyzes conversion of lactate into pyruvate [catalytic activity: (S)-lactate + 2 ferricytochrome C = pyruvate + 2 ferrocytochrome C].
  
  
 
0.924
mez
[NAD] dependent malate oxidoreductase Mez; Catalizes the oxidative decarboxylation of malate into pyruvate, important for a wide range of metabolic pathways [catalytic activity: (S)-malate + NAD(+) = pyruvate + CO(2) + NADH].
    
 0.916
porA
Pyruvate:ferredoxin oxidoreductase, PorA, alpha subunit; Function unknown, probably involved in cellular metabolism.
    
 0.916
pca
Pyruvate carboxylase Pca; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.910
mez_1
[NAD] dependent malate oxidoreductase Mez_1; Catalizes the oxidative decarboxylation of malate into pyruvate, important for a wide range of metabolic pathways [catalytic activity: (S)-malate + NAD(+) = pyruvate + CO(2) + NADH].
    
 0.909
porB
Pyruvate:ferredoxin oxidoreductase PorB, beta subunit; Function unknown, probably involved in cellular metabolism.
    
 0.908
MMAR_3410
Pyruvate dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.907
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.