Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MMAR_2995Conserved hypothetical transmembrane protein; Function unknown. possibly involved in signal transduction mechanisms. (294 aa)    
Predicted Functional Partners:
MMAR_2993
Conserved membrane protein.
 
    
0.542
fdxA_2
Ferredoxin FdxA_2; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
       0.542
MMAR_0859
The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general 'stress endurance' activity.
  
     0.523
MMAR_3476
Conserved hypothetical protein.
 
  
 0.520
MMAR_3479
Sensor part of a two-component regulatory system.
 
  
 0.507
devS
Sensor part of the two-component regulatory system DevR/DevS. thought to control HspX|Acr expression.
 
  
 0.497
MMAR_2997
The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.478
MMAR_2996
Conserved hypothetical protein.
       0.463
MMAR_1518
Conserved protein.
 
  
 0.453
MMAR_0944
Conserved hypothetical protein.
 
  
 0.450
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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