STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMAR_3720FAD-dependent oxidoreductase; Function unknown, probably involved in cellular metabolism. (392 aa)    
Predicted Functional Partners:
MMAR_3721
Conserved hypothetical glycosyl hydrolase.
       0.617
MMAR_3719
Conserved hypothetical protein.
       0.582
MMAR_2628
Conserved hypothetical protein.
  
  
 0.475
pksG
Hydroxymethylglutaryl-coenzyme A synthase, PksG; Part of the mevalonate pathway for isoprenoid synthesis: conversion: acetyl-CoA + H(2)O + acetoacetyl- CoA <=> (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.
   
  
 0.417
erg3
Membrane-bound C-5 sterol desaturase Erg3; Involved in lipid desaturation.
   
 
 0.415
erg3_2
Membrane-bound C-5 sterol desaturase Erg3_2; Involved in lipid desaturation.
   
 
 0.415
erg3_1
Membrane-bound C-5 sterol desaturase Erg3_1; Involved in lipid desaturation.
   
 
 0.415
ribA1
Involved in riboflavin biosynthesis [catalytic activity : GTP + 3 H(2)O = formate + 2,5-diamino-6-hydroxy- 4-(5-phosphoribosylamino)pyrimidine + diphosphate]; In the N-terminal section; belongs to the DHBP synthase family.
  
  
 0.412
MMAR_0278
Conserved hypothetical protein.
  
  
 0.409
MMAR_3214
Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase; HMGR is a tightly regulated enzyme, which catalyzes the synthesis of coenzyme A and mevalonate in isoprenoid synthesis. in mammals, this is the rate limiting committed step in cholesterol biosynthesis. bacteria, such as pseudomonas mevalonii, which rely solely on mevalonate for their carbon source, catalyze the reverse reaction, using an NAD-dependent HMGR to deacetylate mevalonate into 3- hydroxy-3-methylglutaryl-CoA.
   
  
 0.407
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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