Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
MMAR_3752Conserved protein; Function unknown but contains aaa ATPase domain containing von willebrand factor type a (vWA) domain. (291 aa)    
Predicted Functional Partners:
MMAR_3751
Conserved hypothetical protein; Function unknown but contains a von willebrand factor type a conserved domain.
 
    0.966
proA
Gamma-glutamyl phosphate reductase protein ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.807
MMAR_0662
Protein containing vWA domain.
 
     0.782
MMAR_0661
Membrane oxidoreductase; Function unknown, probably involved in cellular metabolism.
 
   
 0.717
coxL
Carbon monoxyde dehydrogenase (large chain), CoxL; Function unknown, probably involved in cellular metabolism [catalytic activity: CO + H(2)O + acceptor = CO(2) + reduced acceptor].
 
   
 0.665
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
   
 
 0.547
MMAR_3755
Adenylate or guanylate cyclase; Generates 3,'5'-cyclic (A/G)mp and diphosphate (or pyrophosphate) from (A/G)tp.
  
    0.539
coxM
Carbon monoxyde dehydrogenase (medium chain), CoxM; Function unknown; probably involved in cellular metabolism [catalytic activity: CO + H(2)O + acceptor = CO(2) + reduced acceptor].
 
   
 0.526
MMAR_3754
Conserved hypothetical membrane protein.
  
  
 0.507
MMAR_3745
Conserved protein; Function unknown, contains DegV-like superfamily domain.
       0.500
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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