STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ppdKPyruvate, phosphate dikinase PpdK; Catalyzes the reversible phosphorylation of pyruvate and phosphate [catalytic activity: ATP + pyruvate + phosphate = AMP + phosphoenolpyruvate + diphosphate]. (556 aa)    
Predicted Functional Partners:
MMAR_3408
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Function unknown; probably involved in cellular metabolism.
 
  
 0.982
pckA
Iron-regulated phosphoenolpyruvate carboxykinase [GTP] PckA; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.935
porA
Pyruvate:ferredoxin oxidoreductase, PorA, alpha subunit; Function unknown, probably involved in cellular metabolism.
    
 0.934
porB
Pyruvate:ferredoxin oxidoreductase PorB, beta subunit; Function unknown, probably involved in cellular metabolism.
 
  
 0.920
aceE_1
Pyruvate dehydrogenase E1 component AceE_1; Involved in energy metabolism; contributes to acetyl-CoA production as part of pyruvate dehydrogenase complex [catalytic activity: pyruvate + lipoamide = S- acetyl-dihydro-lipoamide + CO(2)].
  
  
 0.918
mez
[NAD] dependent malate oxidoreductase Mez; Catalizes the oxidative decarboxylation of malate into pyruvate, important for a wide range of metabolic pathways [catalytic activity: (S)-malate + NAD(+) = pyruvate + CO(2) + NADH].
  
 
 0.916
mez_1
[NAD] dependent malate oxidoreductase Mez_1; Catalizes the oxidative decarboxylation of malate into pyruvate, important for a wide range of metabolic pathways [catalytic activity: (S)-malate + NAD(+) = pyruvate + CO(2) + NADH].
  
 
 0.916
eno
Enolase Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.914
pykA
Pyruvate kinase PykA; Produces phosphoenol pyruvate in glycolysis [catalytic activity : ATP + pyruvate = ADP + phosphoenolpyruvate]; Belongs to the pyruvate kinase family.
    
 0.912
pca
Pyruvate carboxylase Pca; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.911
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.