Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMAR_4902Conserved hypothetical regulatory protein; Function unknown; belongs to the LysR family of transcriptional regulators. (304 aa)    
Predicted Functional Partners:
MMAR_4903
Conserved hypothetical integral membrane protein.
 
  
 0.735
MMAR_1555
Transcriptional regulatory protein.
 
  
 0.561
MMAR_0229
Conserved hypothetical protein.
   
  
 0.558
rpoA
DNA-directed RNA polymerase (alpha chain), RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.541
gltB
Ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB; Probably involved in glutamate biosynthesis [catalytic activity: 2 L-glutamate + NADP(+) = L-glutamine + 2-oxoglutarate + NADPH].
     
 0.521
rpoB
DNA-directed RNA polymerase, beta subunit, RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.484
MMAR_1725
Transcriptional regulatory protein; Involved in transcriptional mechanism.
   
  
 0.477
oxyS
Oxidative stress response regulatory protein OxyS; Could effect functions of OxyR during evolution; Belongs to the LysR transcriptional regulatory family.
  
   
 0.453
MMAR_0249
Transcriptional regulatory protein (possibly TetR-family); Possibly involved in transcriptional mechanism.
    
 
 0.451
MMAR_4219
Involved in transcriptional mechanism.
    
 
 0.444
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.