STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fadD19_1fatty-acid-CoA ligase FadD19_1; Catalyzes the activation of long-chain fatty acids as acyl- coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3- oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26-oyl-CoA. (550 aa)    
Predicted Functional Partners:
echA19
enoyl-CoA hydratase EchA19; Oxidizes fatty acids using specific components [catalytic activity: (3S)-3-hydroxyacyl-CoA = TRANS-2(or 3)-enoyl-CoA + H(2)O].
 
 
 0.927
ltp4
Lipid transfer protein or keto acyl-CoA thiolase Ltp4; Function unknown, probably involved in lipid metabolism.
 
 
 0.917
ltp3
Lipid carrier protein or keto acyl-CoA thiolase Ltp3; Function unknown, probably involved in lipid metabolism.
 
 
 0.873
MMAR_5000
Conserved hypothetical fructosamine kinase-like protein.
       0.865
MMAR_5006
Conserved hypothetical protein; Function unknown, contains a C-term predicted nucleic-acid-binding domain.
 
  
 0.788
fadE29
acyl-CoA dehydrogenase FadE29; Function unknown, but involved in lipid degradation.
 
  
 0.776
fadA5
acetyl-CoA acetyltransferase FadA5; Function unknown, but involved in lipid degradation [catalytic activity: 2 acetyl-CoA = CoA + acetoacetyl- CoA]; Belongs to the thiolase-like superfamily. Thiolase family.
 
 
 0.733
fadE28
acyl-CoA dehydrogenase FadE28; Function unknown, but involved in lipid degradation.
 
  
 0.724
MMAR_5028
Conserved hypothetical protein; Function unknown, potential role in lipid metabolism. contains thioesterase/thiol ester dehydrase- isomerase superfamily domain.
 
   
 0.723
MMAR_4839
Transcriptional regulatory protein (TetR- family); Involved in transcriptional mechanism.
 
   
 0.722
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.