Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
echA19enoyl-CoA hydratase EchA19; Oxidizes fatty acids using specific components [catalytic activity: (3S)-3-hydroxyacyl-CoA = TRANS-2(or 3)-enoyl-CoA + H(2)O]. (274 aa)    
Predicted Functional Partners:
ltp4
Lipid transfer protein or keto acyl-CoA thiolase Ltp4; Function unknown, probably involved in lipid metabolism.
 
 0.954
ltp3
Lipid carrier protein or keto acyl-CoA thiolase Ltp3; Function unknown, probably involved in lipid metabolism.
 
 0.945
fadA5
acetyl-CoA acetyltransferase FadA5; Function unknown, but involved in lipid degradation [catalytic activity: 2 acetyl-CoA = CoA + acetoacetyl- CoA]; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.925
fadD19_1
fatty-acid-CoA ligase FadD19_1; Catalyzes the activation of long-chain fatty acids as acyl- coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3- oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26-oyl-CoA.
 
 
 0.914
fadE29
acyl-CoA dehydrogenase FadE29; Function unknown, but involved in lipid degradation.
 
 0.887
MMAR_4547
Thiolase; Function unknown, but supposed involvement in lipid metabolism.
 
 0.885
echA8_3
enoyl-CoA dehydratase, EchA8_3; Oxidizes fatty acids using specific components [catalytic activity: (3S)-3-hydroxyacyl-CoA = TRANS-2(or 3)-enoyl-CoA + H(2)O].
  
     0.769
fas
Involved in lipid metabolism. fatty acid synthase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH.
  
 0.756
fadD17
fatty-acid-CoA synthetase FadD17; Catalyzes the activation of long-chain fatty acids as acyl- coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension.
  
 
 0.750
fadE28
acyl-CoA dehydrogenase FadE28; Function unknown, but involved in lipid degradation.
 
 0.747
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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