STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMAR_5479Hydrolase; Function unknown, probably involved in cellular metabolism. (406 aa)    
Predicted Functional Partners:
MMAR_5233
N-acetylmuramoyl-L-alanine amidase; Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.
  
 
 0.978
murA
UDP-N-acetylglucosamine 1- carboxyvinyltransferase MurA; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
   
 0.816
MMAR_5375
Conserved hypothetical secreted protein.
  
  
 0.784
iipA
Mycobacterial invasion and intracellular persistence protein, IipA; Similar to a hypothetical invasion protein. possibly an exported protein with unusually long signal sequence. NLP/P60 family protein.
 
  
 0.763
trxC
Thioredoxin participates in various redox reactions through the reversible oxidation of its active center dithiol, to a disulfide, & catalyzes dithiol-disulfide exchange reactions. forms together with thioredoxin reductase and NADPH a redox active system which donates electrons to a wide variety of different metabolic process (by similarity). seems regulated by SigH.
   
 
 0.728
MMAR_4555
Conserved hypothetical protein.
  
     0.712
MMAR_3223
Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
  
     0.673
MMAR_4229
Conserved hypothetical protein.
 
  
 0.655
trxB2
Thioredoxin reductase TrxB2; Enzyme that catalyse the reduction of disulphides by pyridine nucleotides through an enzyme disulphide and a flavin. seems regulated by SigH. [catalytic activity: NADPH + oxidized thioredoxin = NADP(+) + reduced thioredoxin].
  
  
 0.640
ponA2
Bifunctional membrane-associated penicillin- binding protein 1A/1B PonA2; Involved in peptidoglycan synthesis (at the final stages), cell wall formation. synthesis of cross-linked peptidoglycan from the lipid intermediates. the enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
   
 
 0.639
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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