Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AHY60875.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (826 aa)    
Predicted Functional Partners:
AHY60876.1
Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.976
AHY60877.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.588
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.531
AHY60526.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.515
AHY60874.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.491
AHY60873.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.423
Your Current Organism:
Stenotrophomonas rhizophila
NCBI taxonomy Id: 216778
Other names: ATCC BAA-473, CCUG 47042, DSM 14405, JCM 13333, S. rhizophila, Stenotrophomonas rhizophila Wolf et al. 2002, strain e-p10
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