STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhC-2Pyruvate dehydrogenase E2 component. (453 aa)    
Predicted Functional Partners:
pdhD
Pyruvate dehydrogenase E3 component.
 
0.999
pdhB
Pyruvate dehydrogenase E1 component subunit beta.
 
 0.999
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.999
lplA
Lipoate protein ligase A.
 
 0.960
adhE
Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.951
pta
Phosphotransacetylase.
  
 
 0.934
AOG60778.1
Formate acetyltransferase.
   
 
 0.921
pflD
Formate C-acetyltransferase.
   
 
 0.921
prsA
Ribose-phosphate pyrophosphokinase.
  
 0.874
AOG59982.1
Hypothetical protein.
  
 
 0.784
Your Current Organism:
Spiroplasma helicoides
NCBI taxonomy Id: 216938
Other names: ATCC 51746, S. helicoides, strain TABS-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.