STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (402 aa)    
Predicted Functional Partners:
OAK68183.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.985
OAK72598.1
16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
   
    0.975
OAK74170.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.823
OAK74053.1
Cysteine desulfurase; Catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.811
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
     
 0.678
OAK67440.1
Thiamine biosynthesis protein MoeB; Catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.615
OAK67511.1
Thiamine biosynthesis protein MoeB; Catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.615
mnmA-2
Thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
 
 0.588
mnmA
Thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
 
 0.587
OAK67849.1
Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
     
 0.577
Your Current Organism:
Bacillus galactosidilyticus
NCBI taxonomy Id: 217031
Other names: B. galactosidilyticus, Bacillus galactosidasius, Bacillus galactosidilyticus Heyndrickx et al. 2004, DSM 15595, LMG 17892, LMG:17892, strain Logan B2188, strain MB 800
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