STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdcB_1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)    
Predicted Functional Partners:
thrC_1
Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.948
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.943
ltaE
Aspartate aminotransferase family protein; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.940
artP-3
Arginine transporter ATP-binding subunit; With ArtMQJI transports arginine across the inner membrane; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.940
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.938
glyA2_1
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.938
trpB_2
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.931
APX74764.1
Serine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.917
trpA_1
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 
 0.916
trpA_2
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 
 0.916
Your Current Organism:
Achromobacter insolitus
NCBI taxonomy Id: 217204
Other names: A. insolitus, API 201-3-84, Achromobacter insolitus Coenye et al. 2003, Achromobacter sp. AR476-2, Achromobacter sp. KCJK1724, Achromobacter sp. KCJK1731, Achromobacter sp. LMG 6003, Achromobacter sp. UBA1170, Achromobacter sp. UBA1582, CCM 7182, CCUG 47057, LMG 6003, LMG:6003, NCTC 13520, strain Gilardi 3038
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