Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APH39618.1Iron-sulfur cluster assembly scaffold protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)    
Predicted Functional Partners:
APH39617.1
Cysteine desulfurase NifS; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.992
nifS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
 0.939
dnaK
Molecular chaperone DnaK; Acts as a chaperone.
  
 0.876
APH38414.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.862
APH38902.1
Cysteine sulfinate desulfinase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
 0.862
APH39616.1
NAD(FAD)-dependent dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.823
APH39528.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.770
APH39973.1
SirA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.754
APH38723.1
Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.750
APH39527.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.749
Your Current Organism:
Methanohalophilus halophilus
NCBI taxonomy Id: 2177
Other names: DSM 3094, INMI Z-7982, Methanihalophilus halophilus, Methanococcus halophilus, OCM 160, Z-7982
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.