Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mioCPutative flavoprotein (initiation of chromosome replication); Similar to Escherichia coli protein MioC SWALL:MIOC_ECOLI (SWALL:P03817) (146 aa) fasta scores: E(): 3.6e-36, 71.23% id in 146 aa, and to Yersinia pestis putative flavoprotein SWALL:AAM83597 (EMBL:AJ414141) (146 aa) fasta scores: E(): 7.7e-38, 72.6% id in 146 aa, and to Salmonella typhimurium, and Salmonella typhi initiation of chromosome replication MioC SWALL:Q8XET7 (EMBL:AE008881) (147 aa) fasta scores: E(): 1.7e-35, 68.7% id in 147 aa. (147 aa)    
Predicted Functional Partners:
cysI
Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.745
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
     
 0.715
entB
Enterobactin synthetase component B (isochorismatase); Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri isochorismatase EntB or EntG or b0595 or z0737 or ecs0634 or sf0509 SWALL:ENTB_ECOLI (SWALL:P15048) (285 aa) fasta scores: E(): 1.1e-69, 63.63% id in 286 aa.
   
    0.551
asnC
AsnC-family transcriptional regulator; Similar to Yersinia pestis regulatory protein AsnC SWALL:Q8ZJT4 (EMBL:AJ414141) (153 aa) fasta scores: E(): 3.5e-48, 86.92% id in 153 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri regulatory protein AsnC SWALL:ASNC_ECOLI (SWALL:P03809) (152 aa) fasta scores: E(): 8e-47, 87.41% id in 151 aa.
  
    0.542
ehpB
Putative phenazine antibiotic biosynthesis protein; Similar to Pseudomonas chlororaphis PhzD SWALL:Q9R9G4 (EMBL:AF195615) (207 aa) fasta scores: E(): 4.5e-38, 47.29% id in 203 aa, and to Pantoea agglomerans EhpB SWALL:AAN40891 (EMBL:AF451953) (209 aa) fasta scores: E(): 1.9e-36, 46.73% id in 199 aa.
  
    0.411
entE
Similar to Escherichia coli enterobactin synthetase component E [includes: 2,3-dihydroxybenzoate-AMP ligase; S-dihydroxybenzoyltransferase] EntE SWALL:ENTE_ECOLI (SWALL:P10378) (536 aa) fasta scores: E(): 1.1e-129, 64.63% id in 540 aa; EC number 7.7.58.
   
    0.402
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.