Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
asnCAsnC-family transcriptional regulator; Similar to Yersinia pestis regulatory protein AsnC SWALL:Q8ZJT4 (EMBL:AJ414141) (153 aa) fasta scores: E(): 3.5e-48, 86.92% id in 153 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri regulatory protein AsnC SWALL:ASNC_ECOLI (SWALL:P03809) (152 aa) fasta scores: E(): 8e-47, 87.41% id in 151 aa. (153 aa)    
Predicted Functional Partners:
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
 0.767
ECA3668
Similar to Bradyrhizobium japonicum transcriptional regulatory protein blr0340 SWALL:BAC45605 (EMBL:AP005936) (167 aa) fasta scores: E(): 1.4e-26, 52.02% id in 148 aa, and to Rhizobium meliloti putative transcription regulator protein r02941 or smc03210 SWALL:Q92LT2 (EMBL:AL591792) (159 aa) fasta scores: E(): 1.6e-20, 45.16% id in 155 aa.
  
     0.767
ECA1157
Similar to Yersinia pestis probable asnc-family regulatory protein ypo3146 or y1038 SWALL:AAM84619 (EMBL:AJ414155) (153 aa) fasta scores: E(): 1.1e-48, 80.13% id in 151 aa, and to Salmonella typhimurium, and Salmonella typhi putative transcriptional regulator ybao or stm0459 or sty0502 SWALL:Q8XGC9 (EMBL:AE008717) (152 aa) fasta scores: E(): 8.9e-47, 78.14% id in 151 aa.
  
     0.764
asnA
Putative asparagine synthetase A; Similar to Escherichia coli aspartate-ammonia ligase AsnA SWALL:ASNA_ECOLI (SWALL:P00963) (330 aa) fasta scores: E(): 2.7e-107, 81.51% id in 330 aa.
 
   
 0.635
mioC
Putative flavoprotein (initiation of chromosome replication); Similar to Escherichia coli protein MioC SWALL:MIOC_ECOLI (SWALL:P03817) (146 aa) fasta scores: E(): 3.6e-36, 71.23% id in 146 aa, and to Yersinia pestis putative flavoprotein SWALL:AAM83597 (EMBL:AJ414141) (146 aa) fasta scores: E(): 7.7e-38, 72.6% id in 146 aa, and to Salmonella typhimurium, and Salmonella typhi initiation of chromosome replication MioC SWALL:Q8XET7 (EMBL:AE008881) (147 aa) fasta scores: E(): 1.7e-35, 68.7% id in 147 aa.
  
    0.542
cas3
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Might be involved in the integration of spacer DNA into the CRISPR cassette. In the central section; belongs to the CRISPR-associated helicase Cas3 family.
      
 0.542
csy3
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated Csy3 family.
      
 0.541
cas6f
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Processes pre-crRNA into individual crRNA units.
      
 0.540
csy2
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated Csy2 family.
      
 0.539
putA
Bifunctional PutA protein [includes: proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
     
 0.521
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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