Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rbsRRibose operon repressor; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ribose operon repressor RbsR SWALL:AAN45274 (EMBL:M13169) (330 aa) fasta scores: E(): 2.9e-90, 68.99% id in 329 aa. (331 aa)    
Predicted Functional Partners:
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
 0.937
rbsD
High affinity ribose transport protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
  
 0.781
rbsC
Ribose transport permease system protein; Similar to Salmonella typhimurium, and Salmonella typhi ABC superfamily RbsC SWALL:Q8XFM3 (EMBL:AE008881) (321 aa) fasta scores: E(): 2.1e-96, 89.02% id in 319 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ribose transport system permease protein RbsC SWALL:RBSC_ECOLI (SWALL:P04984) (321 aa) fasta scores: E(): 2.3e-96, 88.71% id in 319 aa.
  
 
 0.739
rbsB
Ribose-binding periplasmic protein; Similar to Salmonella typhimurium, and Salmonella typhi D-ribose-binding periplasmic protein precursor RbsB SWALL:RBSB_SALTY (SWALL:P02926) (296 aa) fasta scores: E(): 4.9e-82, 84.4% id in 295 aa, and to Escherichia coli D-ribose-binding periplasmic protein precursor RbsB SWALL:RBSB_ECOLI (SWALL:P02925) (296 aa) fasta scores: E(): 1.8e-81, 84.06% id in 295 aa.
 
 
0.650
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
    
 
 0.634
udk
Uridine kinase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri uridine kinase Udk or b2066 or c2593 or z3234 or ecs2873 or sf2130 SWALL:URK_ECOLI (SWALL:P31218) (213 aa) fasta scores: E(): 3e-70, 87.32% id in 213 aa.
     
 0.597
proY
Similar to Salmonella typhimurium proline-specific permease ProY or stm0400 SWALL:PROY_SALTY (SWALL:P37460) (456 aa) fasta scores: E(): 7.4e-145, 82.78% id in 453 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 proline-specific permease ProY or b0402 or c0512 or z0500 or ecs0452 SWALL:PROY_ECOLI (SWALL:P77327) (457 aa) fasta scores: E(): 4.3e-145, 82.56% id in 453 aa.
      
 0.571
galU
UTP--glucose-1-phosphate uridylyltransferase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri UTP--glucose-1-phosphate uridylyltransferase GalU or b1236 or c1700 or z2012 or ecs1738 or sf1236 SWALL:GALU_ECOLI (SWALL:P25520) (301 aa) fasta scores: E(): 4.5e-98, 85.08% id in 295 aa, and to Erwinia chrysanthemi GalU protein galU SWALL:Q93KA5 (EMBL:AJ410309) (303 aa) fasta scores: E(): 1.1e-106, 92.69% id in 301 aa.
   
 
 0.508
lacZ
Beta-galactosidase; Similar to Escherichia coli beta-galactosidase LacZ or b0344 SWALL:BGAL_ECOLI (SWALL:P00722) (1023 aa) fasta scores: E(): 0, 64.84% id in 1024 aa; Belongs to the glycosyl hydrolase 2 family.
     
 0.484
rbsA
Ribose transport ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
  
 
 0.472
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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