STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemNSimilar to Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN SWALL:HEMN_ECOLI (SWALL:P32131) (457 aa) fasta scores: E(): 3.5e-152, 80.96% id in 457 aa; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (457 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.979
hemF
Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
    
 0.962
hemG
Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa.
  
 
 0.952
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
  
 0.694
ompW
Outer membrane protein W; Similar to Escherichia coli, and Shigella flexneri outer membrane protein W precursor OmpW or b1256 or sf1259 SWALL:OMPW_ECOLI (SWALL:P21364) (212 aa) fasta scores: E(): 7.2e-54, 62.26% id in 212 aa.
 
  
 0.680
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
     
 0.519
ECA3193
Putative protease; Similar to Yersinia pestis putative protease ypo2855 or y1379 SWALL:Q8ZCV5 (EMBL:AJ414154) (464 aa) fasta scores: E(): 9.6e-156, 84.92% id in 451 aa, and to Salmonella typhimurium, and Salmonella typhi putative protease yegq or stm2136 or sty2365 SWALL:Q8XFD2 (EMBL:AE008795) (453 aa) fasta scores: E(): 1.8e-153, 83.48% id in 454 aa.
 
    0.518
fnr
Fumarate and nitrate reduction regulatory protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri fumarate and nitrate reduction regulatory protein Fnr or NirR or b1334 or c1807 or z2433 or ecs1915 or sf1836 SWALL:FNR_ECOLI (SWALL:P03019) (250 aa) fasta scores: E(): 2.9e-89, 94.73% id in 247 aa.
 
  
 0.477
narX
Nitrate/nitrite sensor kinase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri nitrate/nitrite sensor protein NarX or NarR or b1222 or z1998 or ecs1727 or sf1225 SWALL:NARX_ECOLI (SWALL:P10956) (598 aa) fasta scores: E(): 1.5e-115, 54.06% id in 603 aa.
  
    0.473
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
   
  
 0.472
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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