| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA0031 | ECA0033 | ECA0031 | ECA0033 | Haloacid dehalogenase-like hydrolase; Similar to Yersinia pestis hypothetical protein SWALL:AAM87347 (EMBL:AJ414141) (196 aa) fasta scores: E(): 4.3e-55, 71.42% id in 196 aa, and to Escherichia coli hypothetical protein YihX SWALL:YIHX_ECOLI (SWALL:P32145) (199 aa) fasta scores: E(): 2.8e-51, 64.61% id in 195 aa. | Putative GNAT-family acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YiiD SWALL:YIID_ECOLI (SWALL:P32148) (329 aa) fasta scores: E(): 1.6e-108, 82.31% id in 311 aa, and to Salmonella typhimurium, and Salmonella typhi putative acetyltransferase YiiD SWALL:Q8XF59 (EMBL:AE008888) (329 aa) fasta scores: E(): 2.7e-107, 81.34% id in 311 aa. | 0.483 |
| ECA0031 | dtd | ECA0031 | ECA0032 | Haloacid dehalogenase-like hydrolase; Similar to Yersinia pestis hypothetical protein SWALL:AAM87347 (EMBL:AJ414141) (196 aa) fasta scores: E(): 4.3e-55, 71.42% id in 196 aa, and to Escherichia coli hypothetical protein YihX SWALL:YIHX_ECOLI (SWALL:P32145) (199 aa) fasta scores: E(): 2.8e-51, 64.61% id in 195 aa. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.611 |
| ECA0031 | typA | ECA0031 | ECA0030 | Haloacid dehalogenase-like hydrolase; Similar to Yersinia pestis hypothetical protein SWALL:AAM87347 (EMBL:AJ414141) (196 aa) fasta scores: E(): 4.3e-55, 71.42% id in 196 aa, and to Escherichia coli hypothetical protein YihX SWALL:YIHX_ECOLI (SWALL:P32145) (199 aa) fasta scores: E(): 2.8e-51, 64.61% id in 195 aa. | Similar to Escherichia coli GTP-binding protein TypA or BipA or b3871 SWALL:TYPA_ECOLI (SWALL:P32132) (591 aa) fasta scores: E(): 1.1e-189, 90.18% id in 591 aa. Found to be a virulence regulator in an enteropathogenic Escherichia coli (PMID: 9622352). | 0.476 |
| ECA0033 | ECA0031 | ECA0033 | ECA0031 | Putative GNAT-family acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YiiD SWALL:YIID_ECOLI (SWALL:P32148) (329 aa) fasta scores: E(): 1.6e-108, 82.31% id in 311 aa, and to Salmonella typhimurium, and Salmonella typhi putative acetyltransferase YiiD SWALL:Q8XF59 (EMBL:AE008888) (329 aa) fasta scores: E(): 2.7e-107, 81.34% id in 311 aa. | Haloacid dehalogenase-like hydrolase; Similar to Yersinia pestis hypothetical protein SWALL:AAM87347 (EMBL:AJ414141) (196 aa) fasta scores: E(): 4.3e-55, 71.42% id in 196 aa, and to Escherichia coli hypothetical protein YihX SWALL:YIHX_ECOLI (SWALL:P32145) (199 aa) fasta scores: E(): 2.8e-51, 64.61% id in 195 aa. | 0.483 |
| ECA0033 | dtd | ECA0033 | ECA0032 | Putative GNAT-family acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YiiD SWALL:YIID_ECOLI (SWALL:P32148) (329 aa) fasta scores: E(): 1.6e-108, 82.31% id in 311 aa, and to Salmonella typhimurium, and Salmonella typhi putative acetyltransferase YiiD SWALL:Q8XF59 (EMBL:AE008888) (329 aa) fasta scores: E(): 2.7e-107, 81.34% id in 311 aa. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.743 |
| ECA2536 | dtd | ECA2536 | ECA0032 | Similar to Yersinia pestis putative iron-sulfur binding protein ypo1417 or y2752 SWALL:Q8ZG89 (EMBL:AJ414148) (370 aa) fasta scores: E(): 1.8e-107, 70.76% id in 366 aa, and to Salmonella typhimurium putative iron-sulfur protein stm1060 SWALL:Q8ZQ74 (EMBL:AE008746) (369 aa) fasta scores: E(): 1.3e-97, 65.04% id in 369 aa. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.414 |
| dtd | ECA0031 | ECA0032 | ECA0031 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | Haloacid dehalogenase-like hydrolase; Similar to Yersinia pestis hypothetical protein SWALL:AAM87347 (EMBL:AJ414141) (196 aa) fasta scores: E(): 4.3e-55, 71.42% id in 196 aa, and to Escherichia coli hypothetical protein YihX SWALL:YIHX_ECOLI (SWALL:P32145) (199 aa) fasta scores: E(): 2.8e-51, 64.61% id in 195 aa. | 0.611 |
| dtd | ECA0033 | ECA0032 | ECA0033 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | Putative GNAT-family acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YiiD SWALL:YIID_ECOLI (SWALL:P32148) (329 aa) fasta scores: E(): 1.6e-108, 82.31% id in 311 aa, and to Salmonella typhimurium, and Salmonella typhi putative acetyltransferase YiiD SWALL:Q8XF59 (EMBL:AE008888) (329 aa) fasta scores: E(): 2.7e-107, 81.34% id in 311 aa. | 0.743 |
| dtd | ECA2536 | ECA0032 | ECA2536 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | Similar to Yersinia pestis putative iron-sulfur binding protein ypo1417 or y2752 SWALL:Q8ZG89 (EMBL:AJ414148) (370 aa) fasta scores: E(): 1.8e-107, 70.76% id in 366 aa, and to Salmonella typhimurium putative iron-sulfur protein stm1060 SWALL:Q8ZQ74 (EMBL:AE008746) (369 aa) fasta scores: E(): 1.3e-97, 65.04% id in 369 aa. | 0.414 |
| dtd | lpxH | ECA0032 | ECA3155 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.437 |
| dtd | relA | ECA0032 | ECA3569 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.422 |
| dtd | spoT | ECA0032 | ECA0038 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.422 |
| dtd | typA | ECA0032 | ECA0030 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | Similar to Escherichia coli GTP-binding protein TypA or BipA or b3871 SWALL:TYPA_ECOLI (SWALL:P32132) (591 aa) fasta scores: E(): 1.1e-189, 90.18% id in 591 aa. Found to be a virulence regulator in an enteropathogenic Escherichia coli (PMID: 9622352). | 0.482 |
| lpxH | dtd | ECA3155 | ECA0032 | UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.437 |
| relA | dtd | ECA3569 | ECA0032 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.422 |
| relA | spoT | ECA3569 | ECA0038 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.974 |
| spoT | dtd | ECA0038 | ECA0032 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.422 |
| spoT | relA | ECA0038 | ECA3569 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.974 |
| typA | ECA0031 | ECA0030 | ECA0031 | Similar to Escherichia coli GTP-binding protein TypA or BipA or b3871 SWALL:TYPA_ECOLI (SWALL:P32132) (591 aa) fasta scores: E(): 1.1e-189, 90.18% id in 591 aa. Found to be a virulence regulator in an enteropathogenic Escherichia coli (PMID: 9622352). | Haloacid dehalogenase-like hydrolase; Similar to Yersinia pestis hypothetical protein SWALL:AAM87347 (EMBL:AJ414141) (196 aa) fasta scores: E(): 4.3e-55, 71.42% id in 196 aa, and to Escherichia coli hypothetical protein YihX SWALL:YIHX_ECOLI (SWALL:P32145) (199 aa) fasta scores: E(): 2.8e-51, 64.61% id in 195 aa. | 0.476 |
| typA | dtd | ECA0030 | ECA0032 | Similar to Escherichia coli GTP-binding protein TypA or BipA or b3871 SWALL:TYPA_ECOLI (SWALL:P32132) (591 aa) fasta scores: E(): 1.1e-189, 90.18% id in 591 aa. Found to be a virulence regulator in an enteropathogenic Escherichia coli (PMID: 9622352). | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.482 |
