STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0033Putative GNAT-family acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YiiD SWALL:YIID_ECOLI (SWALL:P32148) (329 aa) fasta scores: E(): 1.6e-108, 82.31% id in 311 aa, and to Salmonella typhimurium, and Salmonella typhi putative acetyltransferase YiiD SWALL:Q8XF59 (EMBL:AE008888) (329 aa) fasta scores: E(): 2.7e-107, 81.34% id in 311 aa. (328 aa)    
Predicted Functional Partners:
entB
Enterobactin synthetase component B (isochorismatase); Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri isochorismatase EntB or EntG or b0595 or z0737 or ecs0634 or sf0509 SWALL:ENTB_ECOLI (SWALL:P15048) (285 aa) fasta scores: E(): 1.1e-69, 63.63% id in 286 aa.
  
 
 0.737
ECA2748
Similar to Yersinia pestis hypothetical protein Ypo1261 SWALL:Q8ZGM6 (EMBL:AJ414147) (75 aa) fasta scores: E(): 4.5e-22, 85.52% id in 76 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yejl or stm2227 or sty2465 SWALL:Q8XEL6 (EMBL:AE008799) (75 aa) fasta scores: E(): 1.6e-19, 78.94% id in 76 aa; Belongs to the UPF0352 family.
  
     0.736
dtd
D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
  
  
 0.722
ECA3065
Similar to Yersinia pestis hypothetical protein Ypo2755 SWALL:Q8ZD37 (EMBL:AJ414153) (92 aa) fasta scores: E(): 6.4e-25, 75% id in 92 aa, and to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein yfcl or b2325 or z3588 or ecs3209 SWALL:YFCL_ECOLI (SWALL:P76496) (92 aa) fasta scores: E(): 1.3e-20, 67.41% id in 89 aa.
  
     0.717
seqA
Putative negative regulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.693
nlpB
Lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.689
ECA4055
Putative exported protein; Similar to Yersinia pestis hypothetical protein ypo0192 or y3973 SWALL:Q8ZJC3 (EMBL:AJ414141) (73 aa) fasta scores: E(): 1.2e-12, 60% id in 65 aa, and to Shigella flexneri orf, conserved hypothetical protein yhev or sf3368 SWALL:AAN44831 (EMBL:AE015345) (66 aa) fasta scores: E(): 4.4e-11, 50% id in 64 aa.
  
     0.681
proQ
ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.
  
     0.649
ECA4174
Similar to Yersinia pestis hypothetical protein ypo3835 or y0395 SWALL:Q8ZAG7 (EMBL:AJ414159) (156 aa) fasta scores: E(): 1.4e-35, 63.39% id in 153 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yigi or b3820 or c4741 or sf3898 SWALL:YIGI_ECOLI (SWALL:P27845) (155 aa) fasta scores: E(): 1.6e-35, 64.9% id in 151 aa.
  
     0.642
ECA1013
Putative lipoprotein; Similar to Escherichia coli, and Escherichia coli O6 hypothetical lipoprotein ygdi precursor ygdi or b2809 or c3380 SWALL:YGDI_ECOLI (SWALL:Q46924) (75 aa) fasta scores: E(): 1.6e-14, 61.11% id in 72 aa, and to Shigella flexneri orf, conserved hypothetical protein ygdi or sf2823 SWALL:AAN44310 (EMBL:AE015296) (76 aa) fasta scores: E(): 4.2e-14, 59.72% id in 72 aa.
  
     0.636
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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