STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0035Putative purine permease; Similar to Yersinia pestis putative membrane permease ypo0034 SWALL:Q8ZJQ8 (EMBL:AJ414141) (461 aa) fasta scores: E(): 1.8e-149, 86.98% id in 461 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 putative purine permease YicE SWALL:YICE_ECOLI (SWALL:P27432) (463 aa) fasta scores: E(): 3.4e-148, 85.65% id in 460 aa. (462 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase catalytic subunit; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri aspartate carbamoyltransferase catalytic chain PyrB or b4245 or c5345 or z5856 or ecs5222 or sf4245 SWALL:PYRB_ECOLI (SWALL:P00479) (310 aa) fasta scores: E(): 7.7e-100, 85.43% id in 309 aa; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.746
ECA0034
Putative exported protein; Similar to Yersinia pestis possible exported protein ypo0033 SWALL:Q8ZJQ9 (EMBL:AJ414141) (569 aa) fasta scores: E(): 1.9e-128, 55.37% id in 558 aa, and to Escherichia coli O6 hypothetical protein YicH SWALL:AAN82916 (EMBL:AE016769) (577 aa) fasta scores: E(): 5.3e-123, 48.92% id in 558 aa.
      0.742
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.742
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.717
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.702
carB
Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 93.56% id in 1072 aa; Belongs to the CarB family.
  
  
 0.684
carA
Carbamoyl-phosphate synthase small chain; Similar to Escherichia coli, and Escherichia coli O157:H7 carbamoyl-phosphate synthase small chain CarA or PyrA or b0032 or z0037 or ecs0035 SWALL:CARA_ECOLI (SWALL:P00907) (382 aa) fasta scores: E(): 2e-130, 85.86% id in 382 aa; Belongs to the CarA family.
  
  
 0.680
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.642
fre
NAD(P)H-flavin reductase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 NAD(P)H-flavin reductase Fre or FlrD or FadI or FsrC or UbiB or b3844 or c4791 or z5365 or ecs4772 SWALL:FRE_ECOLI (SWALL:P23486) (232 aa) fasta scores: E(): 5.8e-71, 75.86% id in 232 aa.
 
  
 0.613
YjcD
Putative permease; Similar to Yersinia pestis putative xanthine/uracil permease ypo3629 or y0239 SWALL:Q8ZB00 (EMBL:AJ414158) (451 aa) fasta scores: E(): 7.4e-142, 87.58% id in 451 aa, and to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein yjcd yjcd or b4064 or z5663 or ecs5046 SWALL:YJCD_ECOLI (SWALL:P32702) (449 aa) fasta scores: E(): 4.7e-133, 82.58% id in 448 aa.
 
  
 0.602
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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