STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0044Similar to Yersinia pestis putative membrane protein ypo4013 SWALL:Q8ZA13 (EMBL:AJ414160) (563 aa) fasta scores: E(): 5e-173, 75.4% id in 557 aa, and to Escherichia coli membrane-protein YhjW SWALL:YHJW_ECOLI (SWALL:P37661) (563 aa) fasta scores: E(): 7.5e-150, 64.99% id in 557 aa. (561 aa)    
Predicted Functional Partners:
lpxT
Putative membrane-bound phosphatase; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.
  
  
 0.931
pmrC
Putative sulfatase; Similar to Pectobacterium carotovorum subsp. carotovorum putative cytoplasmic membrane protein PmrC pmrC SWALL:CAE47078 (EMBL:AJ583007) (548 aa) fasta scores: E(): 4.1e-202, 93.79% id in 548 aa, and to Escherichia coli hypothetical protein yjdb or b4114 SWALL:YJDB_ECOLI (SWALL:P30845) (547 aa) fasta scores: E(): 1.2e-128, 59.29% id in 538 aa.
  
  
0.931
pagP
Putative antimicrobial peptide resistance and lipid A acylation protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.
  
  
 0.922
arnT
Dolichyl-phosphate-mannose-protein mannosyltransferase-family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.
  
 
 0.918
msbB
Lipid A biosynthesis (KDO)2-(lauroyl)-lipid iva acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.
     
 0.907
flk
Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
  
     0.720
ECA1784
Conserved hypothetical protein; Similar to Salmonella typhimurium putative cytoplasmic protein ycep or stm1161 SWALL:Q8ZQ21 (EMBL:AE008750) (84 aa) fasta scores: E(): 1.1e-21, 67.85% id in 84 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical protein ycep or b1060 or c1327 SWALL:YCEP_ECOLI (SWALL:P75927) (84 aa) fasta scores: E(): 1.1e-21, 67.85% id in 84 aa.
  
     0.665
ECA2253
Putative exported protein; Similar to Yersinia pseudotuberculosis hypothetical 14.2 kDa protein orf9 SWALL:Q93AP0 (EMBL:AF418982) (124 aa) fasta scores: E(): 8.4e-19, 45.52% id in 123 aa, and to Salmonella typhimurium, and Salmonella typhi putative periplasmic protein ynfb or stm1503 or sty1560 SWALL:Q8XEU2 (EMBL:AE008765) (113 aa) fasta scores: E(): 3.1e-18, 52.52% id in 99 aa; Belongs to the UPF0482 family.
  
     0.660
ECA4404
Similar to Yersinia pestis putative lipoprotein ypo4086 or y4103 SWALL:Q8Z9V4 (EMBL:AJ414160) (112 aa) fasta scores: E(): 2.8e-19, 55.35% id in 112 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein yidq precursor yidq or b3688 or sf3775 SWALL:YIDQ_ECOLI (SWALL:P31454) (110 aa) fasta scores: E(): 1.2e-15, 46.55% id in 116 aa.
  
     0.590
ECA1163
Conserved hypothetical lipoprotein; Similar to Salmonella typhimurium glycoprotein/polysaccharide metabolism ybay or stm0465 SWALL:Q8ZRB1 (EMBL:AE008717) (189 aa) fasta scores: E(): 4e-30, 50.78% id in 191 aa, and to Salmonella typhi hypothetical lipoprotein Sty0509 sty0509 SWALL:Q8Z8U2 (EMBL:AL627266) (189 aa) fasta scores: E(): 6.1e-30, 50.26% id in 189 aa.
  
     0.584
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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