STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uspAUniversal stress protein A; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri universal stress protein A UspA or b3495 or c4293 or z4895 or ecs4367 or sf3526 SWALL:USPA_ECOLI (SWALL:P28242) (143 aa) fasta scores: E(): 6.7e-47, 94.36% id in 142 aa. (145 aa)    
Predicted Functional Partners:
zapB
Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
  
 0.774
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.770
ompN
Similar to Escherichia coli outer membrane protein N precursor OmpN or b1377 SWALL:OMPN_ECOLI (SWALL:P77747) (377 aa) fasta scores: E(): 1.1e-76, 53.86% id in 388 aa.
  
  
 0.769
mukF
Killing factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.765
smp
Putative membrane protein; Similar to Escherichia coli, and Shigella flexneri protein Smp precursor Smp or b4387 or sf4419 SWALL:SMP_ECOLI (SWALL:P18838) (214 aa) fasta scores: E(): 3.9e-52, 65.72% id in 213 aa.
  
   
 0.750
asmA
Putative outer membrane assembly protein; Similar to Escherichia coli protein AsmA precursor AsmA or b2064 SWALL:ASMA_ECOLI (SWALL:P28249) (617 aa) fasta scores: E(): 2.2e-107, 47.74% id in 620 aa.
  
     0.749
ECA0304
Similar to Yersinia pestis putative membrane protein ypo3565 SWALL:AAM83730 (EMBL:AJ414157) (134 aa) fasta scores: E(): 1.5e-41, 87.97% id in 133 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YhcB SWALL:YHCB_ECOLI (SWALL:P39436) (134 aa) fasta scores: E(): 5.6e-34, 80.31% id in 127 aa.
  
     0.746
ftsN
Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
    0.739
helD
Helicase IV; Similar to Escherichia coli helicase IV HelD or b0962 SWALL:HELD_ECOLI (SWALL:P15038) (684 aa) fasta scores: E(): 1.6e-197, 69.29% id in 684 aa.
  
   
 0.725
rof
Modulator of rho-dependent transcription termination; Similar to Escherichia coli, and Shigella flexneri Rof protein or b0189 or sf0179 SWALL:ROF_ECOLI (SWALL:P52098) (84 aa) fasta scores: E(): 3.4e-22, 70.23% id in 84 aa, and to Salmonella typhimurium modulator of rho-dependent transcription termination Rof or stm0237 SWALL:Q8ZRN4 (EMBL:AE008706) (86 aa) fasta scores: E(): 2.9e-20, 66.27% id in 86 aa.
  
    0.722
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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