STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0052Conserved hypothetcial protein; Similar to Pseudomonas aeruginosa hypothetical protein Pa4186 SWALL:Q9HWJ5 (EMBL:AE004835) (439 aa) fasta scores: E(): 1.9e-60, 39.58% id in 432 aa. (437 aa)    
Predicted Functional Partners:
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
  
 
 0.962
glnA
Glutamine synthetase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri glutamine synthetase GlnA or b3870 or c4819 or z5406 or ecs4792 or sf3940 SWALL:GLNA_ECOLI (SWALL:P06711) (468 aa) fasta scores: E(): 3e-170, 90.17% id in 468 aa.
  
 
 0.751
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.624
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
 0.616
gcvT
Glycine cleavage system T protein (aminomethyltransferase); The glycine cleavage system catalyzes the degradation of glycine.
  
 0.604
gabT
Similar to Escherichia coli 4-aminobutyrate aminotransferase GabT or b2662 SWALL:GABT_ECOLI (SWALL:P22256) (426 aa) fasta scores: E(): 1.7e-83, 53.6% id in 416 aa, and to Escherichia coli 4-aminobutyrate aminotransferase GoaG or b1302 SWALL:GOAG_ECOLI (SWALL:P50457) (421 aa) fasta scores: E(): 7e-115, 68.57% id in 420 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.589
ECA2056
Similar to Yersinia pestis putative ABC transporter permease ypo2842 SWALL:Q8ZCW6 (EMBL:AJ414154) (421 aa) fasta scores: E(): 2.8e-118, 72.4% id in 424 aa, and to Pseudomonas aeruginosa probable permease of ABC transporter pa0605 SWALL:Q9I5T3 (EMBL:AE004497) (415 aa) fasta scores: E(): 4.5e-85, 54.47% id in 402 aa.
 
  
 0.589
ECA2060
Similar to Rhizobium meliloti putative aminotransferase ra0973 or sma1761 SWALL:Q92YB1 (EMBL:AE007283) (438 aa) fasta scores: E(): 7.6e-92, 58.13% id in 418 aa, and to Agrobacterium tumefaciens pyridoxal phosphate aminotransferase atu5251 or agr_pat_358 SWALL:Q8UK72 (EMBL:AE008947) (464 aa) fasta scores: E(): 3.4e-74, 51.09% id in 411 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.585
gdhA
Similar to Escherichia coli NADP-specific glutamate dehydrogenase GdhA or b1761 SWALL:DHE4_ECOLI (SWALL:P00370) (447 aa) fasta scores: E(): 7.7e-145, 85.01% id in 447 aa; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.578
ECA4378
Similar to Rhizobium meliloti putative aminotransferase ra0973 or sma1761 SWALL:Q92YB1 (EMBL:AE007283) (438 aa) fasta scores: E(): 1.2e-86, 51.61% id in 434 aa, and to Agrobacterium tumefaciens pyridoxal phosphate aminotransferase atu5251 or agr_pat_358 SWALL:Q8UK72 (EMBL:AE008947) (464 aa) fasta scores: E(): 6.4e-78, 47.85% id in 443 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.578
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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