Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA0057Similar to Escherichia coli probable RNA polymerase sigma factor FecI or b4293 SWALL:FECI_ECOLI (SWALL:P23484) (173 aa) fasta scores: E(): 2.2e-25, 46.38% id in 166 aa; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa)    
Predicted Functional Partners:
ECA0058
Transmembrane sensor; Similar to Escherichia coli protein FecR or b4292 SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 3.1e-33, 36.04% id in 319 aa.
 
 
 0.958
fecR
iron(III) dicitrate sensor protein; Similar to Escherichia coli protein FecR or b4292 SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 7.6e-87, 69.55% id in 312 aa, and to Shigella flexneri 2a FecR SWALL:AAL08457 (EMBL:AF326777) (317 aa) fasta scores: E(): 7.6e-87, 69.55% id in 312 aa.
 
 
 0.908
rseA
sigma-E factor negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases [...]
  
 
 0.864
ECA1273
Putative sensor protein; Similar to Escherichia coli protein FecR or b4292 SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 2.9e-18, 30.09% id in 309 aa, and to Pseudomonas aeruginosa probable transmembrane sensor pa0471 SWALL:Q9I647 (EMBL:AE004485) (323 aa) fasta scores: E(): 8.9e-27, 32.58% id in 313 aa.
 
 
 0.835
ECA0814
Putative iron sensor protein; Similar to Escherichia coli protein FecR SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 4.1e-27, 33.01% id in 315 aa, and to Pseudomonas putida PupR protein SWALL:Q52209 (EMBL:X77918) (324 aa) fasta scores: E(): 3.3e-23, 29.9% id in 321 aa, and to Bordetella avium RhuR SWALL:Q8L1U8 (EMBL:AY095952) (307 aa) fasta scores: E(): 3.3e-17, 27.12% id in 317 aa.
 
 
 0.828
ECA1539
Similar to Pseudomonas aeruginosa probable transmembrane sensor pa3409 SWALL:Q9HYJ6 (EMBL:AE004762) (328 aa) fasta scores: E(): 2.2e-40, 42.68% id in 328 aa, and to Pseudomonas putida transmembrane sensor, putative pp4607 SWALL:AAN70180 (EMBL:AE016791) (326 aa) fasta scores: E(): 2.6e-25, 36.13% id in 321 aa.
 
 
 0.826
fecA
iron(III) dicitrate transport protein; Similar to Escherichia coli iron FecA or b4291 SWALL:FECA_ECOLI (SWALL:P13036) (774 aa) fasta scores: E(): 0, 80.56% id in 782 aa, and to Pseudomonas aeruginosa FecA or pa3901 SWALL:Q9HXB2 (EMBL:AE004807) (784 aa) fasta scores: E(): 1.6e-196, 62.43% id in 788 aa.
  
  
 0.759
ECA1540
ECF sigma factor; Similar to Pseudomonas aeruginosa putative RNA polymerase sigma factor pa3410 SWALL:Q9HYJ5 (EMBL:AE004762) (171 aa) fasta scores: E(): 9.6e-18, 41.76% id in 170 aa, and to Pseudomonas putida RNA polymerase sigma-70 factor, ECF subfamily pp1008 SWALL:AAN66633 (EMBL:AE016777) (170 aa) fasta scores: E(): 1.7e-11, 36.52% id in 167 aa.
  
     0.756
ECA0056
Putative TonB-dependent heme receptor; Similar to Bordetella avium BhuR SWALL:Q8L1U7 (EMBL:AY095952) (855 aa) fasta scores: E(): 8.3e-14, 23.68% id in 874 aa, and to Pasteurella multocida HemR SWALL:Q9CN63 (EMBL:AE006093) (742 aa) fasta scores: E(): 1.5e-143, 51.04% id in 717 aa.
 
  
 0.697
ECA4115
Similar to Ralstonia solanacearum probable ferric siderophore receptor protein rsp0414 or rs00871 SWALL:Q8XSQ3 (EMBL:AL646078) (746 aa) fasta scores: E(): 2.3e-136, 51.09% id in 734 aa, and to Vibrio anguillarum ferric anguibactin receptor precursor fatA SWALL:FATA_VIBAN (SWALL:P11461) (726 aa) fasta scores: E(): 3.5e-79, 35.45% id in 722 aa.
  
  
 0.665
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.