STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtlRMannitol operon repressor; Similar to Escherichia coli, and Escherichia coli O6 mannitol operon repressor MtlR or b3601 or c4418 SWALL:MTLR_ECOLI (SWALL:P36563) (195 aa) fasta scores: E(): 2.6e-47, 74.15% id in 178 aa. (200 aa)    
Predicted Functional Partners:
mtlA
Similar to Escherichia coli PTS system, mannitol-specific IIabc component MtlA or b3599 SWALL:PTMA_ECOLI (SWALL:P00550) (637 aa) fasta scores: E(): 1.1e-188, 81.63% id in 637 aa.
 
   
 0.865
fumA
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
  0.819
ECA0090
Similar to Yersinia pestis hypothetical protein ypo4065 SWALL:AAM87627 (EMBL:AJ414160) (118 aa) fasta scores: E(): 6.1e-24, 67.52% id in 117 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YibL SWALL:YIBL_ECOLI (SWALL:P36564) (120 aa) fasta scores: E(): 2.8e-21, 63.63% id in 121 aa.
 
     0.801
ptsH
PTS system phosphocarrier protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri phosphocarrier protein Hpr or b2415 or c2950 or z3681 or ecs3287 or stm2431 or sty2667 or t0426 or sf2470 SWALL:PTHP_ECOLI (SWALL:P07006) (85 aa) fasta scores: E(): 1e-27, 97.64% id in 85 aa.
    
 
 0.776
mtlD
Similar to Escherichia coli mannitol-1-phosphate 5-dehydrogenase MtlD or b3600 SWALL:MTLD_ECOLI (SWALL:P09424) (382 aa) fasta scores: E(): 5.7e-108, 77.48% id in 382 aa.
 
  
 0.772
wecH
Putative membrane protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.
  
     0.726
ECA4004
Similar to Yersinia pestis hypothetical protein ypo0237 or y4018 SWALL:Q8ZJ84 (EMBL:AJ414141) (66 aa) fasta scores: E(): 3.9e-18, 74.24% id in 66 aa, and to Escherichia coli hypothetical protein yhdl or b3291.1 SWALL:YHDL_ECOLI (SWALL:P36675) (72 aa) fasta scores: E(): 4.3e-16, 60.87% id in 69 aa.
  
     0.702
ECA1841
Similar to Escherichia coli hypothetical protein ydiv or b1707 SWALL:YDIV_ECOLI (SWALL:P76204) (237 aa) fasta scores: E(): 3.5e-23, 36.17% id in 235 aa, and to Shigella flexneri orf, conserved hypothetical protein ydiv or sf1524 SWALL:AAN43114 (EMBL:AE015175) (237 aa) fasta scores: E(): 3.1e-22, 35.74% id in 235 aa.
  
     0.694
flk
Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
  
     0.692
pgpB
Phosphatidylglycerophosphatase B; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri phosphatidylglycerophosphatase B PgpB or b1278 or z2529 or ecs1851 or sf1282 SWALL:PGPB_ECOLI (SWALL:P18201) (254 aa) fasta scores: E(): 6.1e-68, 61.75% id in 251 aa.
  
     0.687
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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