STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fdhDPutative formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (277 aa)    
Predicted Functional Partners:
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
 0.965
ECA1964
Putative molybdopterin oxidoreductase; Similar to Alcaligenes eutrophus CbbbC SWALL:P72261 (EMBL:U60056) (757 aa) fasta scores: E(): 2.9e-139, 50.66% id in 758 aa, and to Pseudomonas putida molybdopterin oxidoreductase, alpha subunit pp0256 SWALL:AAN65887 (EMBL:AE016775) (781 aa) fasta scores: E(): 3e-184, 60% id in 760 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.954
fdhF
Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 
 0.876
ECA1507
Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 1.3e-194, 66.52% id in 699 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 
 0.861
fdnG
Similar to Escherichia coli formate dehydrogenase, nitrate-inducible, major subunit FdnG or b1474 SWALL:FDNG_ECOLI (SWALL:P24183) (1015 aa) fasta scores: E(): 0, 69.75% id in 1015 aa.
 
 
 0.834
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 
 
 0.734
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.728
hyfG
Similar to Escherichia coli hydrogenase-4 component G HyfG or b2487 SWALL:HYFG_ECOLI (SWALL:P77329) (555 aa) fasta scores: E(): 3.1e-128, 78.03% id in 569 aa.
     
 0.725
sodA
Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.722
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 0.699
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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