STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
expISimilar to Erwinia carotovora autoinducer synthesis protein CarI or HslI SWALL:CARI_ERWCA (SWALL:P33880) (216 aa) fasta scores: E(): 1.1e-85, 97.22% id in 216 aa, and to Erwinia carotovora autoinducer synthesis protein ExpI SWALL:EXPI_ERWCA (SWALL:P33882) (217 aa) fasta scores: E(): 9.2e-65, 72.94% id in 207 aa, and to Erwinia chrysanthemi AhlI SWALL:Q8KUJ8 (EMBL:AF448800) (212 aa) fasta scores: E(): 6.5e-54, 62.26% id in 212 aa. (216 aa)    
Predicted Functional Partners:
expR
Quorum-sensing transcriptional regulator; Similar to Pectobacterium carotovorum subsp. betavasculorum LuxR homolog EcbR SWALL:O30346 (EMBL:AF001050) (242 aa) fasta scores: E(): 3.8e-85, 93.38% id in 242 aa, and to Erwinia chrysanthemi transcriptional activator protein EchR SWALL:ECHR_ERWCH (SWALL:Q46967) (250 aa) fasta scores: E(): 3.6e-54, 58.61% id in 244 aa, and to Erwinia carotovora transcriptional activator protein ExpR SWALL:EXPR_ERWCA (SWALL:Q47189) (245 aa) fasta scores: E(): 1.5e-56, 61.57% id in 244 aa. Also similar to ECA1561 (67.839%% in 199 aa overlap).
 
   
 0.890
ECA3917
LuxR-family transcriptional regulator; Similar to Escherichia coli genes, complete cds, strain:b171 SWALL:Q93RC7 (EMBL:AB052736) (143 aa) fasta scores: E(): 0.18, 27.04% id in 122 aa.
  
  
 0.773
ECA1561
Quorum-sensing transcriptional regulator; Similar to Erwinia chrysanthemi transcriptional activator protein EchR SWALL:ECHR_ERWCH (SWALL:Q46967) (250 aa) fasta scores: E(): 5e-67, 72.35% id in 246 aa, and to Erwinia carotovora transcriptional activator protein ExpR SWALL:EXPR_ERWCA (SWALL:Q47189) (245 aa) fasta scores: E(): 1.3e-57, 59.5% id in 242 aa. Also similar to ECA0106 (ExpR) (67.839% in 199 aa overlap).
 
   
 0.766
prtW
Metalloprotease; Similar to Pectobacterium carotovorum subsp. carotovorum metalloprotease PrtW SWALL:Q9RB20 (EMBL:AF141295) (473 aa) fasta scores: E(): 4.7e-142, 84.51% id in 478 aa, and to Erwinia chrysanthemi secreted protease C precursor PrtC SWALL:PRTX_ERWCH (SWALL:P19144) (478 aa) fasta scores: E(): 5.8e-116, 66.03% id in 471 aa.
  
   
 0.599
hor
Global regulator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.
  
   
 0.586
luxS
Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
      
 0.558
flhD
Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
      
 0.550
osmB
Osmotically inducible lipoprotein B; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri osmotically inducible lipoprotein B precursor OsmB or b1283 or c1753 or z2523 or ecs1856 or sf1287 SWALL:OSMB_ECOLI (SWALL:P17873) (72 aa) fasta scores: E(): 5.7e-13, 73.52% id in 68 aa.
  
     0.549
ECA0613
Similar to Salmonella typhi hypothetical protein sty4665 SWALL:Q8Z1C5 (EMBL:AL627283) (529 aa) fasta scores: E(): 3.7e-24, 32.5% id in 523 aa, and to Pseudomonas syringae hypothetical 70.0 kDa protein SWALL:Q8RL93 (EMBL:AY083467) (638 aa) fasta scores: E(): 1.4e-12, 25.24% id in 622 aa.
      
 0.542
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
  
   
 0.531
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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