Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
expRQuorum-sensing transcriptional regulator; Similar to Pectobacterium carotovorum subsp. betavasculorum LuxR homolog EcbR SWALL:O30346 (EMBL:AF001050) (242 aa) fasta scores: E(): 3.8e-85, 93.38% id in 242 aa, and to Erwinia chrysanthemi transcriptional activator protein EchR SWALL:ECHR_ERWCH (SWALL:Q46967) (250 aa) fasta scores: E(): 3.6e-54, 58.61% id in 244 aa, and to Erwinia carotovora transcriptional activator protein ExpR SWALL:EXPR_ERWCA (SWALL:Q47189) (245 aa) fasta scores: E(): 1.5e-56, 61.57% id in 244 aa. Also similar to ECA1561 (67.839%% in 199 aa overlap). (242 aa)    
Predicted Functional Partners:
expI
Similar to Erwinia carotovora autoinducer synthesis protein CarI or HslI SWALL:CARI_ERWCA (SWALL:P33880) (216 aa) fasta scores: E(): 1.1e-85, 97.22% id in 216 aa, and to Erwinia carotovora autoinducer synthesis protein ExpI SWALL:EXPI_ERWCA (SWALL:P33882) (217 aa) fasta scores: E(): 9.2e-65, 72.94% id in 207 aa, and to Erwinia chrysanthemi AhlI SWALL:Q8KUJ8 (EMBL:AF448800) (212 aa) fasta scores: E(): 6.5e-54, 62.26% id in 212 aa.
 
  
 0.987
pmeB
Similar to Erwinia chrysanthemi pectinesterase B precursor PemB SWALL:PMEB_ERWCH (SWALL:Q47474) (433 aa) fasta scores: E(): 8.6e-100, 65.48% id in 394 aa, and to Erwinia carotovora pectinesterase b pemB SWALL:PMEB_ERWCA (SWALL:P55743) (178 aa) fasta scores: E(): 7.6e-61, 91.47% id in 176 aa.
     
 0.539
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Similar to Escherichia coli bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase] PurH or b4006 SWALL:PUR9_ECOLI (SWALL:P15639) (529 aa) fasta scores: E(): 3.7e-184, 88.84% id in 529 aa.
     
 0.520
ECA2640
Similar to Bacillus halodurans hypothetical protein Bh1883 SWALL:Q9KBP2 (EMBL:AP001513) (365 aa) fasta scores: E(): 7.6e-68, 49.45% id in 364 aa, and to Listeria innocua hypothetical protein Lin0474 SWALL:Q92EI5 (EMBL:AL596165) (366 aa) fasta scores: E(): 2e-64, 46.32% id in 367 aa.
     
 0.492
ECA3222
Conserved hypothetical protein; Similar to Pseudomonas aeruginosa PilF protein SWALL:Q51526 (EMBL:L49434) (198 aa) fasta scores: E(): 4.5e-07, 28.4% id in 169 aa, and to Yersinia pestis putative fimbrial biogenesis protein ypo2881 or y1351 SWALL:Q8ZCT4 (EMBL:AJ414154) (249 aa) fasta scores: E(): 4.2e-62, 71.91% id in 235 aa.
 
     0.492
ECA4351
Similar to Yersinia pestis putative membrane protein ypo3819 or y0411 SWALL:Q8ZAI2 (EMBL:AJ414159) (208 aa) fasta scores: E(): 7e-55, 66.98% id in 209 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein yhhn or stm3575 or sty4236 SWALL:Q8XH18 (EMBL:AE008864) (208 aa) fasta scores: E(): 5.2e-51, 63.63% id in 209 aa.
  
     0.484
luxS
Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
      
 0.479
kdgR
Pectin degradation repressor; Similar to Pectobacterium carotovorum subsp. atrosepticum KdgR repressor kdgR SWALL:Q8KM23 (EMBL:AJ504847) (263 aa) fasta scores: E(): 5.4e-99, 97.33% id in 263 aa, and to Erwinia chrysanthemi pectin degradation repressor protein KdgR SWALL:KDGR_ERWCH (SWALL:P37728) (305 aa) fasta scores: E(): 2.8e-92, 91.25% id in 263 aa.
      
 0.471
nosA
TonB dependent receptor; Similar to Pseudomonas stutzeri NosA protein precursor NosA SWALL:Q00620 (EMBL:M60717) (683 aa) fasta scores: E(): 9.3e-150, 57.39% id in 669 aa, and to Yersinia pestis putative membrane receptor protein ypo0164 or y3948 SWALL:Q8ZJE5 (EMBL:AJ414141) (686 aa) fasta scores: E(): 4.6e-177, 64.46% id in 667 aa.
  
     0.465
sun
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
      
 0.465
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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