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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene co-occurrence
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[Homology]
Score
dfpDNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (425 aa)    
Predicted Functional Partners:
KdtB
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
 
 0.988
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
  
 0.976
coaA
Pantothenate kinase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 pantothenate kinase CoaA or Rts or PanK or b3974 or c4933 or z5545 or ecs4901 SWALL:COAA_ECOLI (SWALL:P15044) (316 aa) fasta scores: E(): 2.3e-100, 83.22% id in 316 aa.
   
 
 0.960
metC
Similar to Escherichia coli cystathionine beta-lyase MetC or b3008 SWALL:METC_ECOLI (SWALL:P06721) (395 aa) fasta scores: E(): 8.3e-124, 73.85% id in 394 aa.
  
 
  0.953
aatA
Similar to Rhizobium meliloti aspartate aminotransferase A AatA or r02325 or smc01578 SWALL:AATA_RHIME (SWALL:Q02635) (400 aa) fasta scores: E(): 5.9e-80, 50.62% id in 399 aa, and to Agrobacterium tumefaciens aspartate aminotransferase A AatA or atu4278 or agr_l_1171 SWALL:Q8U821 (EMBL:AE009356) (412 aa) fasta scores: E(): 7.9e-115, 72.04% id in 397 aa.
  
  0.952
mazG
Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa.
  
  
  0.950
cysK
Cysteine synthase A; Similar to Escherichia coli, and Escherichia coli O157:H7 cysteine synthase A CysK or CysZ or b2414 or z3680 or ecs3286 SWALL:CYSK_ECOLI (SWALL:P11096) (322 aa) fasta scores: E(): 1.4e-100, 89.13% id in 322 aa; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.946
ECA1156
Similar to Yersinia pestis putative pyridoxal-phosphate dependent protein ypo3147 or y1037 SWALL:Q8ZC75 (EMBL:AJ414155) (346 aa) fasta scores: E(): 1.4e-117, 83.47% id in 345 aa, and to Salmonella typhimurium putative cysteine synthase/cystathionine beta-synthase stm0458 SWALL:Q8ZRB5 (EMBL:AE008717) (351 aa) fasta scores: E(): 1.6e-105, 76.38% id in 343 aa.
    
  0.946
ECA1293
Similar to Yersinia pestis putative aspartate/glutamate racemase ypo2758 SWALL:Q8ZD34 (EMBL:AJ414153) (231 aa) fasta scores: E(): 2.5e-58, 67.54% id in 228 aa, and to Salmonella typhi hypothetical protein Sty3159 SWALL:Q8Z402 (EMBL:AL627277) (235 aa) fasta scores: E(): 1.6e-49, 55.89% id in 229 aa.
    
  0.945
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 
 0.944
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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