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mutM protein (Pectobacterium atrosepticum) - STRING interaction network
"mutM" - Formamidopyrimidine-DNA glycosylase in Pectobacterium atrosepticum
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
mutMFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3’- and 5’-phosphates (269 aa)    
Predicted Functional Partners:
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family (208 aa)
 
   
  0.902
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (929 aa)
   
   
  0.772
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1294 aa)
 
   
  0.710
mutY
Similar to Escherichia coli A/G-specific adenine glycosylase MutY or MicA or b2961 SWALL-MUTY_ECOLI (SWALL-P17802) (350 aa) fasta scores- E()- 3.8e-114, 75.64% id in 349 aa, and to Yersinia pestis adenine glycosylase MutY or y3339 SWALL-AAM86889 (EMBL-AE013935) (415 aa) fasta scores- E()- 1.4e-124, 81.42% id in 350 aa (368 aa)
   
 
  0.676
ybeY
Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3’ terminus of the 16S rRNA (159 aa)
 
 
  0.648
rpmB
50S ribosomal protein L28; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157-H7, and Shigella flexneri 50S ribosomal protein L28 RpmB or b3637 or c4461 or z5061 or ecs4512 or sf3676 SWALL-RL28_ECOLI (SWALL-P02428) (77 aa) fasta scores- E()- 3.3e-29, 93.5% id in 77 aa; Belongs to the bacterial ribosomal protein bL28 family (78 aa)
         
  0.647
rpmG
50S ribosomal protein L33; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157-H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri 50S ribosomal protein L33 SWALL-RL33_ECOLI (SWALL-P02436) (54 aa) fasta scores- E()- 1.6e-19, 96.29% id in 54 aa; Belongs to the bacterial ribosomal protein bL33 family (55 aa)
         
  0.637
ECA0149
Similar to Yersinia pestis putative sugar transferase RafQ SWALL-Q8ZJC7 (EMBL-AJ414141) (326 aa) fasta scores- E()- 8.7e-82, 60.06% id in 323 aa, and to Serratia marcescens putative heptosyliii transferase WaaQ SWALL-Q9X979 (EMBL-U52844) (337 aa) fasta scores- E()- 7.2e-12, 26.23% id in 343 aa, and to Escherichia coli WaaQ SWALL-Q9R9D5 (EMBL-AF019746) (340 aa) fasta scores- E()- 3.2e-08, 23.25% id in 301 aa (324 aa)
              0.636
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (211 aa)
   
   
  0.608
ECA2558
Similar to Yersinia pestis putative membrane protein ypo1394 or y2778 SWALL-Q8ZGB0 (EMBL-AJ414148) (763 aa) fasta scores- E()- 7.2e-161, 50.19% id in 763 aa, and to Salmonella typhi putative competence-related protein sty0984 SWALL-Q8Z802 (EMBL-AL627268) (754 aa) fasta scores- E()- 7.2e-126, 42.52% id in 762 aa (757 aa)
 
     
  0.588
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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