STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0149Similar to Yersinia pestis putative sugar transferase RafQ SWALL:Q8ZJC7 (EMBL:AJ414141) (326 aa) fasta scores: E(): 8.7e-82, 60.06% id in 323 aa, and to Serratia marcescens putative heptosyliii transferase WaaQ SWALL:Q9X979 (EMBL:U52844) (337 aa) fasta scores: E(): 7.2e-12, 26.23% id in 343 aa, and to Escherichia coli WaaQ SWALL:Q9R9D5 (EMBL:AF019746) (340 aa) fasta scores: E(): 3.2e-08, 23.25% id in 301 aa. (324 aa)    
Predicted Functional Partners:
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
    
 
 0.887
waaF
Similar to Escherichia coli ADP-heptose--LPS heptosyltransferase II RfaF or WaaF or b3620 SWALL:RFAF_ECOLI (SWALL:P37692) (348 aa) fasta scores: E(): 6.2e-108, 74.41% id in 344 aa, and to Serratia marcescens heptosyltransferase II WaaF SWALL:Q936B7 (EMBL:U52844) (348 aa) fasta scores: E(): 7e-115, 79.36% id in 344 aa.
 
  
 0.814
rfaE
ADP-heptose synthase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.
 
  
 0.656
ECA0293
Similar to Yersinia pestis hypothetical protein ypo3577 SWALL:Q8ZB48 (EMBL:AJ414157) (328 aa) fasta scores: E(): 2e-101, 81.59% id in 326 aa, and to Escherichia coli hypothetical protein Yrbh SWALL:YRBH_ECOLI (SWALL:P45395) (328 aa) fasta scores: E(): 2e-95, 78.08% id in 324 aa.
 
   
 0.617
ECA3273
Putative ferredoxin; Similar to Escherichia coli O6 putative ferredoxin-like protein yfhl or c3086 SWALL:AAN81535 (EMBL:AE016764) (86 aa) fasta scores: E(): 4.5e-28, 82.55% id in 86 aa, and to Salmonella typhimurium putative ferredoxin yfhl or stm2576 SWALL:Q8ZN20 (EMBL:AE008817) (86 aa) fasta scores: E(): 2.3e-27, 79.06% id in 86 aa.
  
   0.603
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
     
 0.581
diaA
Putative phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily.
 
   
 0.555
lpcA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
 
   
 0.541
ECA3523
Similar to Yersinia pestis hypothetical protein ypo1074 or y3103 SWALL:Q8ZH37 (EMBL:AJ414146) (188 aa) fasta scores: E(): 1.8e-57, 79.03% id in 186 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yaed or b0200 or z0212 or ecs0202 or sf0191 SWALL:AAN41853 (EMBL:D15061) (191 aa) fasta scores: E(): 2.8e-57, 80.43% id in 184 aa.
 
   
 0.531
kdtX
Similar to Serratia marcescens lipopolysaccharide core biosynthesis glycosyl transferase KdtX SWALL:KDTX_SERMA (SWALL:Q54435) (257 aa) fasta scores: E(): 3.5e-66, 65.72% id in 248 aa, and to Yersinia enterocolitica glucosyl-transferase WaaE SWALL:Q8RSW8 (EMBL:AY075041) (257 aa) fasta scores: E(): 3.5e-66, 65.72% id in 248 aa.
 
  
 0.522
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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