STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdtA3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (425 aa)    
Predicted Functional Partners:
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 0.998
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.984
waaF
Similar to Escherichia coli ADP-heptose--LPS heptosyltransferase II RfaF or WaaF or b3620 SWALL:RFAF_ECOLI (SWALL:P37692) (348 aa) fasta scores: E(): 6.2e-108, 74.41% id in 344 aa, and to Serratia marcescens heptosyltransferase II WaaF SWALL:Q936B7 (EMBL:U52844) (348 aa) fasta scores: E(): 7e-115, 79.36% id in 344 aa.
 
  
 0.973
waaC
Similar to Escherichia coli lipopolysaccharide heptosyltransferase-1 RfaC or WaaC or Rfa-2 or b3621 SWALL:RFAC_ECOLI (SWALL:P24173) (319 aa) fasta scores: E(): 6.6e-89, 71.47% id in 319 aa, and to Serratia marcescens heptosyltransferase i WaaC SWALL:Q936B6 (EMBL:U52844) (321 aa) fasta scores: E(): 8.9e-98, 76.25% id in 320 aa.
 
  
 0.969
waaQ
Similar to Escherichia coli lipopolysaccharide core biosynthesis glycosyl transferase RfaQ or WaaQ or b3632 SWALL:RFAQ_ECOLI (SWALL:P25742) (344 aa) fasta scores: E(): 1.3e-65, 52.69% id in 334 aa, and to Salmonella typhimurium lipopolysaccharide core biosynthesis, modification of heptose region of core RfaQ or stm3723 SWALL:O68270 (EMBL:AF026386) (344 aa) fasta scores: E(): 1.2e-64, 51.79% id in 334 aa.
  
 0.967
ddg
Putative lipid A biosynthesis acyltransferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
 
  
 0.958
htrB
Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
 
  
 0.949
waaI
Similar to Escherichia coli lipopolysaccharide 1,3-galactosyltransferase RfaI or WaaI or b3627 SWALL:RFAI_ECOLI (SWALL:P27128) (339 aa) fasta scores: E(): 7.7e-60, 44.21% id in 337 aa, and to Salmonella typhimurium lipopolysaccharide 1,3-galactosyltransferase RfaI or WaaI or stm3718 SWALL:RFAI_SALTY (SWALL:P19816) (337 aa) fasta scores: E(): 2e-64, 48.21% id in 336 aa.
 
  
 0.927
waaJ
Similar to Escherichia coli lipopolysaccharide 1,2-glucosyltransferase RfaJ or WaaJ or b3626 SWALL:RFAJ_ECOLI (SWALL:P27129) (338 aa) fasta scores: E(): 4.4e-63, 49.69% id in 330 aa, and to Salmonella typhimurium lipopolysaccharide 1,2-glucosyltransferase RfaJ or WaaJ or stm3717 SWALL:RFAJ_SALTY (SWALL:P19817) (336 aa) fasta scores: E(): 5.6e-66, 53.98% id in 326 aa.
 
  
 0.925
arnT
Dolichyl-phosphate-mannose-protein mannosyltransferase-family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.
 
  
 0.925
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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