STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
waaFSimilar to Escherichia coli ADP-heptose--LPS heptosyltransferase II RfaF or WaaF or b3620 SWALL:RFAF_ECOLI (SWALL:P37692) (348 aa) fasta scores: E(): 6.2e-108, 74.41% id in 344 aa, and to Serratia marcescens heptosyltransferase II WaaF SWALL:Q936B7 (EMBL:U52844) (348 aa) fasta scores: E(): 7e-115, 79.36% id in 344 aa. (355 aa)    
Predicted Functional Partners:
waaC
Similar to Escherichia coli lipopolysaccharide heptosyltransferase-1 RfaC or WaaC or Rfa-2 or b3621 SWALL:RFAC_ECOLI (SWALL:P24173) (319 aa) fasta scores: E(): 6.6e-89, 71.47% id in 319 aa, and to Serratia marcescens heptosyltransferase i WaaC SWALL:Q936B6 (EMBL:U52844) (321 aa) fasta scores: E(): 8.9e-98, 76.25% id in 320 aa.
 
0.998
waaL1
O-antigen ligase; Similar to Escherichia coli O-antigen ligase RfaL or WaaL or b3622 SWALL:RFAL_ECOLI (SWALL:P27243) (419 aa) fasta scores: E(): 1.2e-28, 29.22% id in 414 aa, and to Serratia marcescens lipid a core:surface polymer ligase WaaL SWALL:Q936B4 (EMBL:U52844) (413 aa) fasta scores: E(): 1.1e-39, 33.76% id in 385 aa. Also similar to ECA0161 (36.735% id. in 392 aa overlap).
  
 
 0.981
rfaD
ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
  
 0.976
waaQ
Similar to Escherichia coli lipopolysaccharide core biosynthesis glycosyl transferase RfaQ or WaaQ or b3632 SWALL:RFAQ_ECOLI (SWALL:P25742) (344 aa) fasta scores: E(): 1.3e-65, 52.69% id in 334 aa, and to Salmonella typhimurium lipopolysaccharide core biosynthesis, modification of heptose region of core RfaQ or stm3723 SWALL:O68270 (EMBL:AF026386) (344 aa) fasta scores: E(): 1.2e-64, 51.79% id in 334 aa.
 
 
0.975
kdtA
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.973
waaG
Similar to Escherichia coli lipopolysaccharide core biosynthesis protein Rfag or WaaG or pcsa or b3631 SWALL:RFAG_ECOLI (SWALL:P25740) (374 aa) fasta scores: E(): 1.2e-87, 58.69% id in 368 aa, and to Salmonella typhimurium lipopolysaccharide core biosynthesis protein Rfag or WaaG or stm3722 SWALL:O68269 (EMBL:AF026386) (374 aa) fasta scores: E(): 1.5e-89, 60.05% id in 368 aa.
 
 
 0.960
ECA3523
Similar to Yersinia pestis hypothetical protein ypo1074 or y3103 SWALL:Q8ZH37 (EMBL:AJ414146) (188 aa) fasta scores: E(): 1.8e-57, 79.03% id in 186 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yaed or b0200 or z0212 or ecs0202 or sf0191 SWALL:AAN41853 (EMBL:D15061) (191 aa) fasta scores: E(): 2.8e-57, 80.43% id in 184 aa.
   
 0.936
waaL2
O-antigen ligase; Similar to Escherichia coli O-antigen ligase RfaL or WaaL or b3622 SWALL:RFAL_ECOLI (SWALL:P27243) (419 aa) fasta scores: E(): 2.7e-28, 30.54% id in 406 aa. Also similar to ECA0162 (36.735% id. in 392 aa overlap).
  
 
 0.921
waaJ
Similar to Escherichia coli lipopolysaccharide 1,2-glucosyltransferase RfaJ or WaaJ or b3626 SWALL:RFAJ_ECOLI (SWALL:P27129) (338 aa) fasta scores: E(): 4.4e-63, 49.69% id in 330 aa, and to Salmonella typhimurium lipopolysaccharide 1,2-glucosyltransferase RfaJ or WaaJ or stm3717 SWALL:RFAJ_SALTY (SWALL:P19817) (336 aa) fasta scores: E(): 5.6e-66, 53.98% id in 326 aa.
  
 
 0.915
waaI
Similar to Escherichia coli lipopolysaccharide 1,3-galactosyltransferase RfaI or WaaI or b3627 SWALL:RFAI_ECOLI (SWALL:P27128) (339 aa) fasta scores: E(): 7.7e-60, 44.21% id in 337 aa, and to Salmonella typhimurium lipopolysaccharide 1,3-galactosyltransferase RfaI or WaaI or stm3718 SWALL:RFAI_SALTY (SWALL:P19816) (337 aa) fasta scores: E(): 2e-64, 48.21% id in 336 aa.
  
 
 0.915
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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