STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (361 aa)    
Predicted Functional Partners:
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
 
 
 0.996
tdcB
Putative threonine dehydratase catabolic; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri threonine dehydratase catabolic TdcB or b3117 or c3875 or z4469 or ecs3997 or sf3157 SWALL:THD2_ECOLI (SWALL:P05792) (329 aa) fasta scores: E(): 9.6e-33, 38.14% id in 312 aa, and to Thermotoga maritima threonine dehydratase catabolic tm0356 SWALL:Q9WYJ1 (EMBL:AE001716) (401 aa) fasta scores: E(): 6.1e-41, 41.32% id in 317 aa.
   
 0.905
ilvA
Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 0.905
ECA2252
Similar to Escherichia coli probable oxidoreductase ydfg or b1539 SWALL:YDFG_ECOLI (SWALL:P39831) (248 aa) fasta scores: E(): 2.3e-73, 78.62% id in 248 aa, and to Salmonella typhimurium, and Salmonella typhi hypothetical oxidoreductase ydfg or stm1511 or sty1550 SWALL:YDFG_SALTY (SWALL:P40864) (248 aa) fasta scores: E(): 2.6e-73, 77.73% id in 247 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.902
thrC
Threonine synthase; Similar to Escherichia coli threonine synthase ThrC or b0004 SWALL:THRC_ECOLI (SWALL:P00934) (428 aa) fasta scores: E(): 4.2e-135, 80.51% id in 426 aa.
     
 0.901
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
 
  
 0.757
ECA3499
Probable amidase; Similar to Yersinia pestis probable amidase ypo3261 or y0928 SWALL:Q8ZBX3 (EMBL:AJ414156) (465 aa) fasta scores: E(): 5.1e-122, 70.11% id in 455 aa, and to Pseudomonas sp. biuret hydrolase atzE SWALL:Q936X3 (EMBL:U66917) (457 aa) fasta scores: E(): 2e-87, 53.09% id in 452 aa.
     
 0.547
ECA0041
Putative membrane protein; No significant database matches.
      
 0.544
ECA4072
ABC transporter ATP-binding protein; Similar to Rhizobium meliloti putative dipeptide transport ATP-binding ABC transporter protein dppf2 or r02409 or smc01529 SWALL:Q92N30 (EMBL:AL591790) (255 aa) fasta scores: E(): 4.6e-46, 53.93% id in 254 aa, and to Agrobacterium tumefaciens ABC transporter, nucleotide binding/ATPase protein atu3456 or agr_l_2744 SWALL:Q8UAB8 (EMBL:AE009276) (259 aa) fasta scores: E(): 4e-46, 53.06% id in 245 aa.
      
 0.544
ECA4465
Putative membrane protein; Similar to Salmonella typhimurium, and Salmonella typhi phage shock protein PspD or stm1687 or sty1374 SWALL:Q8XEN8 (EMBL:AE008775) (72 aa) fasta scores: E(): 2.4, 31.08% id in 74 aa, and to Salmonella typhi phage shock protein D PspD or t1592 SWALL:AAO69223 (EMBL:AE016839) (72 aa) fasta scores: E(): 2.4, 31.08% id in 74 aa.
      
 0.544
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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