Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysESerine acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri serine acetyltransferase CysEor b3607 or c4429 or z5034 or ecs4485 or sf3646 SWALL:CYSE_ECOLI (SWALL:P05796) (273 aa) fasta scores: E(): 5.1e-90, 86.08% id in 273 aa, and to Yersinia pestis serine acetyltransferase CysE SWALL:Q8ZJM4 (EMBL:AJ414141) (273 aa) fasta scores: E(): 1.5e-92, 89.37% id in 273 aa. (273 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase A; Similar to Escherichia coli, and Escherichia coli O157:H7 cysteine synthase A CysK or CysZ or b2414 or z3680 or ecs3286 SWALL:CYSK_ECOLI (SWALL:P11096) (322 aa) fasta scores: E(): 1.4e-100, 89.13% id in 322 aa; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.996
cysM
Cysteine synthase B; Similar to Escherichia coli cysteine synthase B CysM SWALL:CYSM_ECOLI (SWALL:P16703) (303 aa) fasta scores: E(): 1e-83, 73.97% id in 292 aa; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.993
ECA1156
Similar to Yersinia pestis putative pyridoxal-phosphate dependent protein ypo3147 or y1037 SWALL:Q8ZC75 (EMBL:AJ414155) (346 aa) fasta scores: E(): 1.4e-117, 83.47% id in 345 aa, and to Salmonella typhimurium putative cysteine synthase/cystathionine beta-synthase stm0458 SWALL:Q8ZRB5 (EMBL:AE008717) (351 aa) fasta scores: E(): 1.6e-105, 76.38% id in 343 aa.
  
 0.989
serB
Phosphoserine phosphatase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri phosphoserine phosphatase SerB or b4388 or z5989 or ecs5346 or sf4420 SWALL:SERB_ECOLI (SWALL:P06862) (322 aa) fasta scores: E(): 5.7e-81, 71.87% id in 320 aa.
    
 0.974
ilvA
Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
 0.970
thrA
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I [includes: aspartokinase I; homoserine dehydrogenase I] thra or thra1 or thra2 or b0002 SWALL:AK1H_ECOLI (SWALL:P00561) (820 aa) fasta scores: E(): 0, 82.41% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
  
 0.964
metL
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase II MetL or MetM or b3940 SWALL:AK2H_ECOLI (SWALL:P00562) (809 aa) fasta scores: E(): 0, 83.12% id in 800 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
  
 0.964
ECA4113
Similar to Streptomyces venezuelae cystathionine beta-synthase cbssV SWALL:Q9EYM7 (EMBL:AF319543) (463 aa) fasta scores: E(): 1.5e-28, 36.81% id in 326 aa, and to Rhizobium fredii Y4xP SWALL:Q8RQB8 (EMBL:AF229441) (336 aa) fasta scores: E(): 1.6e-81, 69.06% id in 333 aa.
 
 0.962
pssA
Similar to Escherichia coli cdp-diacylglycerol--serine O-phosphatidyltransferase PssA or Pss or b2585 SWALL:PSS_ECOLI (SWALL:P23830) (451 aa) fasta scores: E(): 6.3e-133, 72.12% id in 452 aa.
  
  
  0.951
sdaA
L-serine dehydratase 1; Similar to Escherichia coli L-serine dehydratase 1 SdaA or b1814 SWALL:SDHL_ECOLI (SWALL:P16095) (454 aa) fasta scores: E(): 5.1e-154, 83.92% id in 454 aa. Also similar to ECA3159 (SdaB) (75.165% id. in 455 aa overlap); Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.950
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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