STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0186Similar to Yersinia pestis hypothetical protein ypo3785 or y0445 SWALL:AAM84034 (EMBL:AJ414158) (276 aa) fasta scores: E(): 7.8e-34, 58.9% id in 275 aa. (260 aa)    
Predicted Functional Partners:
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
    
   0.902
nuoM
Similar to Escherichia coli, and Escherichia coli O157:H7 NADH-quinone oxidoreductase chain M NuoM or b2277 or z3536 or ecs3161 SWALL:NUOM_ECOLI (SWALL:P31978) (509 aa) fasta scores: E(): 8.2e-174, 86.18% id in 514 aa.
    
 0.798
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
  0.750
ECA2021
Similar to Yersinia pestis sulfate transporter y2285 SWALL:Q8D0E3 (EMBL:AE013831) (565 aa) fasta scores: E(): 3.6e-172, 80.56% id in 561 aa, and to Escherichia coli, and Escherichia coli O157:H7 putative sulfate transporter ychm or b1206 or z1977 or ecs1711 SWALL:YCHM_ECOLI (SWALL:P40877) (550 aa) fasta scores: E(): 1.4e-156, 76.61% id in 543 aa.
   
   0.646
ECA2958
Putative sulfate transporter; Similar to Corynebacterium efficiens putative transport protein ce2200 SWALL:BAC19010 (EMBL:AP005221) (555 aa) fasta scores: E(): 1e-89, 51.49% id in 503 aa, and to Micrococcus sp. 28 putative integral membrane transporter SWALL:Q8VPP9 (EMBL:AY034092) (515 aa) fasta scores: E(): 2.1e-94, 51.19% id in 502 aa.
   
   0.646
udp
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
    
  0.641
nuoB
NADH-quinone oxidoreductase chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
    
   0.472
ECA0687
Putative DNA-binding protein; Similar to Yersinia pestis hypothetical protein ypo3514 SWALL:AAM84258 (EMBL:AJ414157) (133 aa) fasta scores: E(): 1.9e-17, 47.32% id in 112 aa and to bacteriophage D3112 transposase A SWALL:Q38013 (EMBL:X87627) (690 aa) fasta scores: E(): 0.00026, 33.69% id in 92 aa.
  
     0.441
nuoN
NADH-quinone oxidoreductase chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
    
   0.423
ECA0969
Similar to Yersinia pestis putative tetr-family regulatory protein ypo3840 or y0390 SWALL:AAM83979 (EMBL:AJ414159) (228 aa) fasta scores: E(): 1.4e-33, 71.36% id in 213 aa, and to Rhizobium loti transcriptional regulator mll3386 SWALL:Q98GC7 (EMBL:AP003001) (219 aa) fasta scores: E(): 3.2e-30, 48.66% id in 187 aa.
  
     0.418
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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