STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (257 aa)    
Predicted Functional Partners:
argC
Putative N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 0.999
argA
Amino-acid acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 amino-acid acetyltransferase ArgA or b2818 or c3412 or z4135 or ecs3675 SWALL:ARGA_ECOLI (SWALL:P08205) (443 aa) fasta scores: E(): 1.7e-149, 85.26% id in 441 aa, and to Yersinia pestis amino-acid acetyltransferase ArgA or ypo1022 or y3162 SWALL:Q8ZH86 (EMBL:AJ414146) (441 aa) fasta scores: E(): 1.5e-152, 88.43% id in 441 aa; Belongs to the acetyltransferase family. ArgA subfamily.
 
 
 0.991
argH
Similar to Escherichia coli argininosuccinate lyase ArgH or b3960 SWALL:ARLY_ECOLI (SWALL:P11447) (457 aa) fasta scores: E(): 1.4e-155, 85.52% id in 456 aa.
 
  
 0.982
argG
Argininosuccinate synthase; Similar to Escherichia coli, and Escherichia coli O6 argininosuccinate synthase ArgG or b3172 or c3929 SWALL:ASSY_ECOLI (SWALL:P22767) (446 aa) fasta scores: E(): 1.2e-162, 91.89% id in 444 aa; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
 
  
 0.942
argE
Similar to Escherichia coli acetylornithine deacetylase ArgE or b3957 SWALL:ARGE_ECOLI (SWALL:P23908) (383 aa) fasta scores: E(): 2.1e-137, 83.02% id in 383 aa; Belongs to the peptidase M20A family. ArgE subfamily.
 
  
 0.883
argD
Acetylornithine/succinyldiaminopimelate aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.865
argI
Ornithine carbamoyltransferase chain I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
  
 0.796
patA
Probable aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
 
  
 0.755
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.738
metL
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase II MetL or MetM or b3940 SWALL:AK2H_ECOLI (SWALL:P00562) (809 aa) fasta scores: E(): 0, 83.12% id in 800 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
  
 0.723
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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