| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA0210 | hemG | ECA0210 | ECA0212 | Similar to Escherichia coli O157:H7 hypothetical protein YigZ SWALL:Q8X8I0 (EMBL:AE005615) (205 aa) fasta scores: E(): 1.9e-44, 63.86% id in 202 aa, and to Escherichia coli hypothetical protein YigZ SWALL:YIGZ_ECOLI (SWALL:P27862) (204 aa) fasta scores: E(): 2.9e-44, 63.86% id in 202 aa. | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | 0.652 |
| ECA0210 | pepQ | ECA0210 | ECA0209 | Similar to Escherichia coli O157:H7 hypothetical protein YigZ SWALL:Q8X8I0 (EMBL:AE005615) (205 aa) fasta scores: E(): 1.9e-44, 63.86% id in 202 aa, and to Escherichia coli hypothetical protein YigZ SWALL:YIGZ_ECOLI (SWALL:P27862) (204 aa) fasta scores: E(): 2.9e-44, 63.86% id in 202 aa. | Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position. | 0.806 |
| ECA0210 | trkH | ECA0210 | ECA0211 | Similar to Escherichia coli O157:H7 hypothetical protein YigZ SWALL:Q8X8I0 (EMBL:AE005615) (205 aa) fasta scores: E(): 1.9e-44, 63.86% id in 202 aa, and to Escherichia coli hypothetical protein YigZ SWALL:YIGZ_ECOLI (SWALL:P27862) (204 aa) fasta scores: E(): 2.9e-44, 63.86% id in 202 aa. | Trk system potassium uptake protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. | 0.695 |
| ECA0882 | hemG | ECA0882 | ECA0212 | Similar to Yersinia pestis hypothetical protein ypo3025 SWALL:Q8ZCG6 (EMBL:AJ414155) (299 aa) fasta scores: E(): 1.3e-91, 75.25% id in 299 aa, and to Escherichia coli hypothetical protein YfeX SWALL:YFEX_ECOLI (SWALL:P76536) (299 aa) fasta scores: E(): 3.6e-79, 67.33% id in 300 aa. | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | 0.602 |
| ECA3009 | hemF | ECA3009 | ECA0874 | Similar to Vibrio parahaemolyticus coproporphyrinogen oxidase homolog PhuW SWALL:Q9XCY7 (EMBL:AF119047) (420 aa) fasta scores: E(): 3.6e-47, 37.87% id in 396 aa, and to Yersinia pestis putative coproporphyrinogen III oxidase ypo0286 or y0547 SWALL:Q8ZJ42 (EMBL:AJ414141) (437 aa) fasta scores: E(): 2.2e-122, 69.1% id in 437 aa. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.544 |
| ECA3009 | hemG | ECA3009 | ECA0212 | Similar to Vibrio parahaemolyticus coproporphyrinogen oxidase homolog PhuW SWALL:Q9XCY7 (EMBL:AF119047) (420 aa) fasta scores: E(): 3.6e-47, 37.87% id in 396 aa, and to Yersinia pestis putative coproporphyrinogen III oxidase ypo0286 or y0547 SWALL:Q8ZJ42 (EMBL:AJ414141) (437 aa) fasta scores: E(): 2.2e-122, 69.1% id in 437 aa. | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | 0.503 |
| hemC | hemF | ECA4188 | ECA0874 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.705 |
| hemC | hemG | ECA4188 | ECA0212 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | 0.505 |
| hemC | hemH | ECA4188 | ECA1181 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.734 |
| hemC | hemN | ECA4188 | ECA0026 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Similar to Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN SWALL:HEMN_ECOLI (SWALL:P32131) (457 aa) fasta scores: E(): 3.5e-152, 80.96% id in 457 aa; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.461 |
| hemC | hemX | ECA4188 | ECA4190 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Similar to Escherichia coli putative uroporphyrin-III C-methyltransferase HemX or b3803 SWALL:HEMX_ECOLI (SWALL:P09127) (393 aa) fasta scores: E(): 5.1e-71, 60.54% id in 370 aa. | 0.891 |
| hemF | ECA3009 | ECA0874 | ECA3009 | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Similar to Vibrio parahaemolyticus coproporphyrinogen oxidase homolog PhuW SWALL:Q9XCY7 (EMBL:AF119047) (420 aa) fasta scores: E(): 3.6e-47, 37.87% id in 396 aa, and to Yersinia pestis putative coproporphyrinogen III oxidase ypo0286 or y0547 SWALL:Q8ZJ42 (EMBL:AJ414141) (437 aa) fasta scores: E(): 2.2e-122, 69.1% id in 437 aa. | 0.544 |
| hemF | hemC | ECA0874 | ECA4188 | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.705 |
| hemF | hemG | ECA0874 | ECA0212 | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | 0.983 |
| hemF | hemH | ECA0874 | ECA1181 | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.750 |
| hemF | hemN | ECA0874 | ECA0026 | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Similar to Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN SWALL:HEMN_ECOLI (SWALL:P32131) (457 aa) fasta scores: E(): 3.5e-152, 80.96% id in 457 aa; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.962 |
| hemG | ECA0210 | ECA0212 | ECA0210 | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | Similar to Escherichia coli O157:H7 hypothetical protein YigZ SWALL:Q8X8I0 (EMBL:AE005615) (205 aa) fasta scores: E(): 1.9e-44, 63.86% id in 202 aa, and to Escherichia coli hypothetical protein YigZ SWALL:YIGZ_ECOLI (SWALL:P27862) (204 aa) fasta scores: E(): 2.9e-44, 63.86% id in 202 aa. | 0.652 |
| hemG | ECA0882 | ECA0212 | ECA0882 | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | Similar to Yersinia pestis hypothetical protein ypo3025 SWALL:Q8ZCG6 (EMBL:AJ414155) (299 aa) fasta scores: E(): 1.3e-91, 75.25% id in 299 aa, and to Escherichia coli hypothetical protein YfeX SWALL:YFEX_ECOLI (SWALL:P76536) (299 aa) fasta scores: E(): 3.6e-79, 67.33% id in 300 aa. | 0.602 |
| hemG | ECA3009 | ECA0212 | ECA3009 | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | Similar to Vibrio parahaemolyticus coproporphyrinogen oxidase homolog PhuW SWALL:Q9XCY7 (EMBL:AF119047) (420 aa) fasta scores: E(): 3.6e-47, 37.87% id in 396 aa, and to Yersinia pestis putative coproporphyrinogen III oxidase ypo0286 or y0547 SWALL:Q8ZJ42 (EMBL:AJ414141) (437 aa) fasta scores: E(): 2.2e-122, 69.1% id in 437 aa. | 0.503 |
| hemG | hemC | ECA0212 | ECA4188 | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.505 |