| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA0210 | fadB | ECA0210 | ECA0208 | Similar to Escherichia coli O157:H7 hypothetical protein YigZ SWALL:Q8X8I0 (EMBL:AE005615) (205 aa) fasta scores: E(): 1.9e-44, 63.86% id in 202 aa, and to Escherichia coli hypothetical protein YigZ SWALL:YIGZ_ECOLI (SWALL:P27862) (204 aa) fasta scores: E(): 2.9e-44, 63.86% id in 202 aa. | Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.591 |
| ECA0210 | hemG | ECA0210 | ECA0212 | Similar to Escherichia coli O157:H7 hypothetical protein YigZ SWALL:Q8X8I0 (EMBL:AE005615) (205 aa) fasta scores: E(): 1.9e-44, 63.86% id in 202 aa, and to Escherichia coli hypothetical protein YigZ SWALL:YIGZ_ECOLI (SWALL:P27862) (204 aa) fasta scores: E(): 2.9e-44, 63.86% id in 202 aa. | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | 0.631 |
| ECA0210 | pepQ | ECA0210 | ECA0209 | Similar to Escherichia coli O157:H7 hypothetical protein YigZ SWALL:Q8X8I0 (EMBL:AE005615) (205 aa) fasta scores: E(): 1.9e-44, 63.86% id in 202 aa, and to Escherichia coli hypothetical protein YigZ SWALL:YIGZ_ECOLI (SWALL:P27862) (204 aa) fasta scores: E(): 2.9e-44, 63.86% id in 202 aa. | Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position. | 0.811 |
| ECA0210 | trkH | ECA0210 | ECA0211 | Similar to Escherichia coli O157:H7 hypothetical protein YigZ SWALL:Q8X8I0 (EMBL:AE005615) (205 aa) fasta scores: E(): 1.9e-44, 63.86% id in 202 aa, and to Escherichia coli hypothetical protein YigZ SWALL:YIGZ_ECOLI (SWALL:P27862) (204 aa) fasta scores: E(): 2.9e-44, 63.86% id in 202 aa. | Trk system potassium uptake protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. | 0.677 |
| ECA0882 | hemG | ECA0882 | ECA0212 | Similar to Yersinia pestis hypothetical protein ypo3025 SWALL:Q8ZCG6 (EMBL:AJ414155) (299 aa) fasta scores: E(): 1.3e-91, 75.25% id in 299 aa, and to Escherichia coli hypothetical protein YfeX SWALL:YFEX_ECOLI (SWALL:P76536) (299 aa) fasta scores: E(): 3.6e-79, 67.33% id in 300 aa. | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | 0.555 |
| cyaA | hemG | ECA4187 | ECA0212 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | 0.477 |
| cyaA | hemX | ECA4187 | ECA4190 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Similar to Escherichia coli putative uroporphyrin-III C-methyltransferase HemX or b3803 SWALL:HEMX_ECOLI (SWALL:P09127) (393 aa) fasta scores: E(): 5.1e-71, 60.54% id in 370 aa. | 0.686 |
| fadB | ECA0210 | ECA0208 | ECA0210 | Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | Similar to Escherichia coli O157:H7 hypothetical protein YigZ SWALL:Q8X8I0 (EMBL:AE005615) (205 aa) fasta scores: E(): 1.9e-44, 63.86% id in 202 aa, and to Escherichia coli hypothetical protein YigZ SWALL:YIGZ_ECOLI (SWALL:P27862) (204 aa) fasta scores: E(): 2.9e-44, 63.86% id in 202 aa. | 0.591 |
| fadB | hemG | ECA0208 | ECA0212 | Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | 0.493 |
| fadB | pepQ | ECA0208 | ECA0209 | Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position. | 0.577 |
| fadB | trkH | ECA0208 | ECA0211 | Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | Trk system potassium uptake protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. | 0.451 |
| hemF | hemG | ECA0874 | ECA0212 | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | 0.929 |
| hemF | hemH | ECA0874 | ECA1181 | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.643 |
| hemF | hemN | ECA0874 | ECA0026 | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Similar to Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN SWALL:HEMN_ECOLI (SWALL:P32131) (457 aa) fasta scores: E(): 3.5e-152, 80.96% id in 457 aa; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.923 |
| hemG | ECA0210 | ECA0212 | ECA0210 | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | Similar to Escherichia coli O157:H7 hypothetical protein YigZ SWALL:Q8X8I0 (EMBL:AE005615) (205 aa) fasta scores: E(): 1.9e-44, 63.86% id in 202 aa, and to Escherichia coli hypothetical protein YigZ SWALL:YIGZ_ECOLI (SWALL:P27862) (204 aa) fasta scores: E(): 2.9e-44, 63.86% id in 202 aa. | 0.631 |
| hemG | ECA0882 | ECA0212 | ECA0882 | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | Similar to Yersinia pestis hypothetical protein ypo3025 SWALL:Q8ZCG6 (EMBL:AJ414155) (299 aa) fasta scores: E(): 1.3e-91, 75.25% id in 299 aa, and to Escherichia coli hypothetical protein YfeX SWALL:YFEX_ECOLI (SWALL:P76536) (299 aa) fasta scores: E(): 3.6e-79, 67.33% id in 300 aa. | 0.555 |
| hemG | cyaA | ECA0212 | ECA4187 | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | 0.477 |
| hemG | fadB | ECA0212 | ECA0208 | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.493 |
| hemG | hemF | ECA0212 | ECA0874 | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.929 |
| hemG | hemH | ECA0212 | ECA1181 | Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.932 |