STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsdRegulator of sigma D; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase. (153 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.899
rpoS
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
  
 
 0.741
ptsH
PTS system phosphocarrier protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri phosphocarrier protein Hpr or b2415 or c2950 or z3681 or ecs3287 or stm2431 or sty2667 or t0426 or sf2470 SWALL:PTHP_ECOLI (SWALL:P07006) (85 aa) fasta scores: E(): 1e-27, 97.64% id in 85 aa.
    
 
 0.715
ECA0332
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YqiB SWALL:AAN44551 (EMBL:D16557) (140 aa) fasta scores: E(): 1.6e-47, 80% id in 140 aa.
  
     0.656
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
   
 
 0.645
wecH
Putative membrane protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.
  
     0.613
nudC
Similar to Escherichia coli NADH pyrophosphatase NudC SWALL:NUDC_ECOLI (SWALL:P32664) (257 aa) fasta scores: E(): 2.2e-77, 70.42% id in 257 aa, and to Yersinia pestis NADH pyrophosphatase NudC SWALL:NUDC_YERPE (SWALL:Q8ZAQ5) (260 aa) fasta scores: E(): 1.3e-84, 75.87% id in 257 aa.
     
 0.599
ECA1841
Similar to Escherichia coli hypothetical protein ydiv or b1707 SWALL:YDIV_ECOLI (SWALL:P76204) (237 aa) fasta scores: E(): 3.5e-23, 36.17% id in 235 aa, and to Shigella flexneri orf, conserved hypothetical protein ydiv or sf1524 SWALL:AAN43114 (EMBL:AE015175) (237 aa) fasta scores: E(): 3.1e-22, 35.74% id in 235 aa.
  
     0.556
ECA0813
RNA polymerase sigma factor; Similar to Bordetella avium RhuI SWALL:Q8L1U9 (EMBL:AY095952) (168 aa) fasta scores: E(): 5.1e-26, 45% id in 160 aa, and to Escherichia coli probable RNA polymerase sigma factor feci feci or b4293 SWALL:FECI_ECOLI (SWALL:P23484) (173 aa) fasta scores: E(): 2.1e-22, 43.94% id in 157 aa; Belongs to the sigma-70 factor family. ECF subfamily.
    
 
 0.547
traF
Putative plasmid transfer protein; Similar to Shigella sonnei TraF protein SWALL:Q9Z4A1 (EMBL:AB021078) (400 aa) fasta scores: E(): 2.9e-81, 55% id in 400 aa, and to Salmonella typhimurium TraF protein SWALL:Q9R2H5 (EMBL:AB027308) (400 aa) fasta scores: E(): 3.4e-81, 54.75% id in 400 aa, and to Escherichia fergusonii TraF SWALL:Q8KR61 (EMBL:AY046057) (401 aa) fasta scores: E(): 1e-61, 44.52% id in 402 aa.
  
     0.545
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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