STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
docSimilar to Bacteriophage P1 death on curing protein Doc SWALL:DOC_BPP1 (SWALL:Q06259) (126 aa) fasta scores: E(): 1.5e-05, 37.61% id in 109 aa, and to Escherichia coli Doc protein Doc SWALL:Q47172 (EMBL:X98141) (126 aa) fasta scores: E(): 1.1e-05, 37.61% id in 109 aa. (156 aa)    
Predicted Functional Partners:
ECA0254
Hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.773
ddlB
D-alanine--D-alanine ligase B; Cell wall formation.
      
 0.579
chpA
Putative growth inhibitory protein; Similar to Escherichia coli, and Escherichia coli O157:H7 PemK-like protein 1 ChpA or MazF or ChpaK or b2782 or z4097 or ecs3642 SWALL:CHPA_ECOLI (SWALL:P33645) (111 aa) fasta scores: E(): 5.2e-31, 72.97% id in 111 aa, and to Deinococcus radiodurans ppgpp-regulated growth inhibitor chpa/mazf, putative dr0417 SWALL:Q9RX98 (EMBL:AE001901) (117 aa) fasta scores: E(): 5e-18, 48.21% id in 112 aa.
      
 0.545
chpR
Suppressor of growth inhibitory protein ChpA; Similar to Escherichia coli, and Escherichia coli O157:H7 PemI-like protein 1 ChpR or MazE or ChpaI or b2783 or z4098 or ecs3643 SWALL:CHPR_ECOLI (SWALL:P18534) (82 aa) fasta scores: E(): 4.6e-09, 38.55% id in 83 aa, and to Bacillus halodurans suppressor of ppgpp-regulated growth inhibitor bh3720 SWALL:Q9K6K9 (EMBL:AP001519) (81 aa) fasta scores: E(): 6.1e-05, 38.75% id in 80 aa.
     
 0.545
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
      
 0.506
mreB
Rod shape-determining protein; Similar to Escherichia coli, Escherichia coli O6, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri rod shape-determining protein MreB or EnvB or RodY or b3251 or c4006 or stm3374 or sty3554 or t3289 or sf3289 SWALL:MREB_ECOLI (SWALL:P13519) (347 aa) fasta scores: E(): 1.7e-117, 97.11% id in 347 aa.
      
 0.496
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.490
mvpA
Putative plasmid protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
     
 0.487
mcK
Putative plasmid-related protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
     
 0.487
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.483
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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