STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fisDNA-binding protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. (98 aa)    
Predicted Functional Partners:
dusB
Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
  
  
 0.957
hda
Conserved hypothetical protein; Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity); Belongs to the DnaA family. HdA subfamily.
  
   
 0.682
hfq
Putative phage-related protein (host factor-I protein); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
 
   
 0.637
ihfB
Integration host factor beta-subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
  
   
 0.634
dusC
Putative dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.
  
  
 0.632
dusA
Putative dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
  
  
 0.632
accC
Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
  
 0.623
crp
Cyclic AMP receptor protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri catabolite gene activator Crp or Cap or Csm or b3357 or c4132 or z4718 or ecs4208 or sf3376 SWALL:CRP_ECOLI (SWALL:P03020) (210 aa) fasta scores: E(): 6.2e-78, 99.04% id in 210 aa, and to Pectobacterium carotovorum subsp. carotovorum CrP SWALL:Q8KJ23 (EMBL:AB090359) (210 aa) fasta scores: E(): 4.6e-78, 99.04% id in 210 aa, and to Erwinia chrysanthemi Crp regulatory protein CrP SWALL:O07097 (EMBL:X89443) (210 aa) fasta scores: E(): 7.2e-77, 97.14% id in 210 aa.
  
   
 0.617
ECA3549
Putative signaling protein; Similar to Vibrio vulnificus response regulator VieA vv21511 SWALL:AAO08375 (EMBL:AE016813) (386 aa) fasta scores: E(): 5.5e-16, 30.04% id in 233 aa, and to Anabaena sp. two-component response regulator alr1230 SWALL:Q8YXI3 (EMBL:AP003585) (403 aa) fasta scores: E(): 7.6e-16, 30.35% id in 224 aa.
    
 
 0.612
ECA0266
Similar to Yersinia pestis putative exported protein ypo3664 SWALL:Q8ZAW7 (EMBL:AJ414158) (638 aa) fasta scores: E(): 3.6e-144, 55.91% id in 642 aa, and to Escherichia coli O6 hypothetical protein YhdA SWALL:AAN82448 (EMBL:AE016767) (646 aa) fasta scores: E(): 1.8e-137, 52.85% id in 649 aa.
   
 
 0.603
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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