STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
cahCarbonic anhydrase; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. (244 aa)    
Predicted Functional Partners:
ECA3327
Putative carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
     
 0.930
rplR
50S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.752
rplE
50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.716
tmcA
Putative acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
   
    0.561
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
       0.525
dusB
Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
  
   0.511
panF
Similar to Escherichia coli sodium/pantothenate symporter panF or b3258 SWALL:PANF_ECOLI (SWALL:P16256) (483 aa) fasta scores: E(): 4.3e-141, 76.79% id in 474 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
       0.507
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
   
  
 0.415
ECA4196
Putative acetyltransferase; Similar to Bacillus subtilis hypothetical protein yxel or lp9D SWALL:YXEL_BACSU (SWALL:P54951) (165 aa) fasta scores: E(): 1.2e-30, 49.69% id in 165 aa, and to Listeria innocua hypothetical protein Lin2444 lin2444 SWALL:Q928T8 (EMBL:AL596172) (178 aa) fasta scores: E(): 1.6e-20, 38.18% id in 165 aa.
  
     0.405
ECA3425
Putative lipoprotein; Similar to Xanthomonas campestris ankyrin-like protein xcc4050 SWALL:Q8P3M1 (EMBL:AE012526) (325 aa) fasta scores: E(): 2.1e-08, 30.68% id in 264 aa, and to Serratia sp. MK1 accessory protein plaS SWALL:Q9X9D9 (EMBL:U37262) (251 aa) fasta scores: E(): 5.5e-07, 25.31% id in 237 aa. Also similar to ECA3424 (83.784% identity in 259 aa overlap).
  
 0.404
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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