STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
cafARibonuclease G; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ribonuclease G CafA or Rng or b3247 or c4001 or z4605 or ecs4119 or sf3285 SWALL:RNG_ECOLI (SWALL:P25537) (488 aa) fasta scores: E(): 4.9e-168, 90.36% id in 488 aa. (489 aa)    
Predicted Functional Partners:
ECA0270
Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
    0.896
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.850
mreC
Rod shape-determining protein; Involved in formation and maintenance of cell shape.
       0.811
mreD
Rod shape-determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
       0.811
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
    
 0.775
rapZ
Putative P-loop ATPase family protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.
 
 
 
 0.763
ECA0272
Similar to Yersinia pestis putative exported protein ypo3670 SWALL:Q8ZAW2 (EMBL:AJ414158) (1307 aa) fasta scores: E(): 0, 56.76% id in 1300 aa, and to Escherichia coli O6 hypothetical protein YhdP SWALL:AAN82440 (EMBL:AE016767) (1266 aa) fasta scores: E(): 2e-213, 54.68% id in 1282 aa.
  
    0.672
tldD
Putative modulator of DNA gyrase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri TldD protein or b3244 or c3999 or sf3283 SWALL:TLDD_ECOLI (SWALL:P46473) (481 aa) fasta scores: E(): 9.6e-150, 82.53% id in 481 aa, and to Salmonella typhimurium, and Salmonella typhi suppresses inhibitory activity of csra tldd or stm3368 or sty3548 SWALL:Q8XFQ3 (EMBL:AE008855) (481 aa) fasta scores: E(): 5.5e-150, 82.74% id in 481 aa. Also similar to ECA1268 (55.297% id. in 472 aa overlap).
       0.529
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.521
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
  
 0.509
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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