STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdrASimilar to Serratia marcescens putative temperature-dependent regulator A TdrA SWALL:Q8VUI0 (EMBL:AB077386) (303 aa) fasta scores: E(): 1.9e-100, 82.5% id in 303 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical transcriptional regulator yhcs or b3243 or c3998 or z4602 or ecs4116 SWALL:YHCS_ECOLI (SWALL:P45691) (309 aa) fasta scores: E(): 2.1e-97, 80.06% id in 311 aa; Belongs to the LysR transcriptional regulatory family. (311 aa)    
Predicted Functional Partners:
sftR
LysR-family transcriptional regulator; Similar to Pseudomonas putida SftR SWALL:Q9WWU4 (EMBL:AF126201) (304 aa) fasta scores: E(): 1.2e-43, 42.19% id in 301 aa, and to Pseudomonas sp. SDS degradation transcriptional activation protein sdsB SWALL:SDSB_PSES9 (SWALL:P52686) (306 aa) fasta scores: E(): 1.3e-30, 36.53% id in 312 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.735
hdfR
LysR-family transcriptional regulator; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.706
oxyR
Similar to Erwinia carotovora hydrogen peroxide-inducible genes activator OxyR SWALL:OXYR_ERWCA (SWALL:P71318) (302 aa) fasta scores: E(): 5.9e-118, 99% id in 302 aa, and to Erwinia chrysanthemi hydrogen peroxide-inducible genes activator OxyR SWALL:OXYR_ERWCH (SWALL:Q9X725) (305 aa) fasta scores: E(): 4.9e-114, 95.68% id in 301 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hydrogen peroxide-inducible genes activator OxyR or MomR or Mor or b3961 or c4922 or z5519 or ecs4890 SWALL:OXYR_ECOLI (SWALL:P11721) (305 aa) fasta scores: E(): 1.3e-106, 89.4% id i [...]
  
     0.702
ECA4427
LysR-family transcriptional regulator; Similar to Agrobacterium tumefaciens regulatory protein NocR or atu6029 or agr_pti_70 SWALL:NOCR_AGRT5 (SWALL:Q00678) (300 aa) fasta scores: E(): 1.4e-28, 35.29% id in 289 aa, and to Rhizobium meliloti octopine catabolism/uptake operon regulatory protein OccR SWALL:OCCR_RHIME (SWALL:P72294) (297 aa) fasta scores: E(): 5.8e-23, 36.58% id in 287 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.693
ECA2713
Similar to Yersinia pestis putative LysR-family transcriptional regulatory protein ypo1503 or y2666 SWALL:AAM86219 (EMBL:AJ414148) (289 aa) fasta scores: E(): 1.1e-90, 79.93% id in 284 aa, and to Pseudomonas putida transcriptional regulator, LysR family pp3152 SWALL:AAN68760 (EMBL:AE016785) (288 aa) fasta scores: E(): 1.2e-58, 53.12% id in 288 aa.
  
     0.675
hexA1
LysR-family transcriptional regulator of motility and virulence; Previously sequenced in Pectobacterium carotovorum subsp. atrosepticum as HexA SWALL:O85276 (EMBL:AF057064) (316 aa) fasta scores: E(): 4.1e-120, 99.68% id in 316 aa, and similar to Erwinia chrysanthemi pectinase gene transcriptional regulator PecT SWALL:PECT_ERWCH (SWALL:P52662) (316 aa) fasta scores: E(): 6.8e-95, 79.36% id in 315 aa. Also identical to ECA3032; Belongs to the LysR transcriptional regulatory family.
  
     0.666
hexA2
LysR-family transcriptional regulator of motility and virulence; Previously sequenced in Pectobacterium carotovorum subsp. atrosepticum as HexA SWALL:O85276 (EMBL:AF057064) (316 aa) fasta scores: E(): 4.1e-120, 99.68% id in 316 aa, and similar to Erwinia chrysanthemi pectinase gene transcriptional regulator PecT SWALL:PECT_ERWCH (SWALL:P52662) (316 aa) fasta scores: E(): 6.8e-95, 79.36% id in 315 aa. Also identical to ECA3030.
  
     0.666
ECA0034
Putative exported protein; Similar to Yersinia pestis possible exported protein ypo0033 SWALL:Q8ZJQ9 (EMBL:AJ414141) (569 aa) fasta scores: E(): 1.9e-128, 55.37% id in 558 aa, and to Escherichia coli O6 hypothetical protein YicH SWALL:AAN82916 (EMBL:AE016769) (577 aa) fasta scores: E(): 5.3e-123, 48.92% id in 558 aa.
  
     0.661
ftsN
Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
    0.648
ECA1447
Putative exported protein; Similar to Escherichia coli hypothetical protein ymcb precursor ymcb or b0985 SWALL:YMCB_ECOLI (SWALL:P75883) (248 aa) fasta scores: E(): 3.6e-08, 31% id in 258 aa, and to Shigella flexneri orf, conserved hypothetical protein ymcb or sf0987 SWALL:AAN42615 (EMBL:AE015127) (248 aa) fasta scores: E(): 3.6e-08, 32.04% id in 259 aa.
  
     0.643
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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