STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0280Similar to Escherichia coli succinate-semialdehyde dehydrogenase [NADP+] GabD or b2661 SWALL:GABD_ECOLI (SWALL:P25526) (482 aa) fasta scores: E(): 8.3e-102, 55.41% id in 480 aa, and to Photorhabdus luminescens Orf17 SWALL:AAO17183 (EMBL:AF346500) (490 aa) fasta scores: E(): 6e-104, 57.74% id in 478 aa. (484 aa)    
Predicted Functional Partners:
gabT
Similar to Escherichia coli 4-aminobutyrate aminotransferase GabT or b2662 SWALL:GABT_ECOLI (SWALL:P22256) (426 aa) fasta scores: E(): 1.7e-83, 53.6% id in 416 aa, and to Escherichia coli 4-aminobutyrate aminotransferase GoaG or b1302 SWALL:GOAG_ECOLI (SWALL:P50457) (421 aa) fasta scores: E(): 7e-115, 68.57% id in 420 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.922
sdhA
Succinate dehydrogenase flavoprotein subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 succinate dehydrogenase flavoprotein subunit SdhA or b0723 or c0801 or z0877 or ecs0748 SWALL:DHSA_ECOLI (SWALL:P10444) (588 aa) fasta scores: E(): 0, 93.19% id in 588 aa; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
   
 0.919
sdhB
Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB or b0724 SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 6.3e-88, 87.81% id in 238 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
 
 0.908
hpcH
Similar to Escherichia coli 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase HpcH or HpaI SWALL:HPAI_ECOLI (SWALL:Q47098) (262 aa) fasta scores: E(): 4.9e-22, 32.4% id in 250 aa; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.905
sdhD
Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
   
 
 0.904
sdhC
Similar to Escherichia coli, and Escherichia coli O157:H7 succinate dehydrogenase cytochrome b-556 subunit SdhC or CybA or b0721 or z0875 or ecs0746 SWALL:DHSC_ECOLI (SWALL:P10446) (129 aa) fasta scores: E(): 1.1e-38, 79.06% id in 129 aa.
   
 
  0.903
gabD
Similar to Escherichia coli succinate-semialdehyde dehydrogenase [NADP+] GabD or b2661 SWALL:GABD_ECOLI (SWALL:P25526) (482 aa) fasta scores: E(): 6e-122, 65.76% id in 482 aa.
  
  
 
0.903
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.880
gltA
Citrate synthase; Similar to Escherichia coli, and Escherichia coli O6 citrate synthase GltA or GluT or IcdB or b0720 or c0796 SWALL:CISY_ECOLI (SWALL:P00891) (427 aa) fasta scores: E(): 3.3e-160, 87.55% id in 426 aa.
  
 0.865
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    
 0.865
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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