STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsNSimilar to Escherichia coli, and Shigella flexneri nitrogen regulatory IIA protein PtsN or RpoP SWALL:PTSN_ECOLI (SWALL:P31222) (163 aa) fasta scores: E(): 1.3e-46, 80.12% id in 156 aa, and to Yersinia pestis phosphotransferase system enzyme IIA PtsN SWALL:AAM83751 (EMBL:AE013615) (164 aa) fasta scores: E(): 6.1e-48, 81.01% id in 158 aa. (157 aa)    
Predicted Functional Partners:
ptsO
Phosphocarrier protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri phosphocarrier protein PtsO or Npr or RpoR or b3206 or c3966 or z4569 or ecs4085 or sf3246 SWALL:PTSO_ECOLI (SWALL:P33996) (90 aa) fasta scores: E(): 5.4e-26, 83.33% id in 90 aa.
 
 
 0.982
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.833
ECA0287
Similar to Klebsiella pneumoniae probable sigma(54) modulation protein SWALL:RP5M_KLEPN (SWALL:P17161) (95 aa) fasta scores: E(): 7e-26, 76.84% id in 95 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri probable sigma (54) modulation protein Yhbh SWALL:RP5M_ECOLI (SWALL:P31221) (95 aa) fasta scores: E(): 2.4e-25, 77.89% id in 95 aa.
  
  
 0.815
fruA
Similar to Escherichia coli pts system, fructose-specific IIbc component FruA or PtsF or b2167 SWALL:PTFB_ECOLI (SWALL:P20966) (563 aa) fasta scores: E(): 1.4e-146, 75.13% id in 567 aa.
 
  
 0.807
rapZ
Putative P-loop ATPase family protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.
  
  
 0.786
ECA0342
PTS system, EIIa component; Similar to Escherichia coli O6 putative phosphotransferase system c4487 SWALL:AAN82923 (EMBL:AE016769) (156 aa) fasta scores: E(): 1.7e-44, 79.73% id in 153 aa, and to Listeria monocytogenes hypothetical protein Lmo2137 lmo2137 SWALL:Q8Y5C8 (EMBL:AL591982) (157 aa) fasta scores: E(): 2.2e-23, 48.99% id in 149 aa.
  
     0.766
ptsP
Similar to Escherichia coli phosphoenolpyruvate-protein phosphotransferase PtsP or b2829 SWALL:PT1P_ECOLI (SWALL:P37177) (748 aa) fasta scores: E(): 1.6e-214, 74.02% id in 747 aa, and to Salmonella typhimurium phosphoenolpyruvate-protein phosphotransferase PtsP or stm3003 SWALL:PT1P_SALTY (SWALL:P37178) (748 aa) fasta scores: E(): 2.6e-215, 73.36% id in 747 aa; Belongs to the PEP-utilizing enzyme family.
  
   
 0.761
mtlA
Similar to Escherichia coli PTS system, mannitol-specific IIabc component MtlA or b3599 SWALL:PTMA_ECOLI (SWALL:P00550) (637 aa) fasta scores: E(): 1.1e-188, 81.63% id in 637 aa.
 
  
0.750
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.744
ECA3349
Similar to Yersinia pestis putative sigma 54 modulation protein ypo3279 SWALL:Q8ZBV5 (EMBL:AJ414156) (120 aa) fasta scores: E(): 3.7e-34, 84.95% id in 113 aa, and to Salmonella typhimurium, and Salmonella typhi ribosome associated factor, stabilizes ribosomes against dissociation yfia or stm2665 or sty2853 SWALL:Q8XEX6 (EMBL:AE008821) (112 aa) fasta scores: E(): 8.3e-31, 79.46% id in 112 aa.
 
  
 0.683
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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