STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ptsNSimilar to Escherichia coli, and Shigella flexneri nitrogen regulatory IIA protein PtsN or RpoP SWALL:PTSN_ECOLI (SWALL:P31222) (163 aa) fasta scores: E(): 1.3e-46, 80.12% id in 156 aa, and to Yersinia pestis phosphotransferase system enzyme IIA PtsN SWALL:AAM83751 (EMBL:AE013615) (164 aa) fasta scores: E(): 6.1e-48, 81.01% id in 158 aa. (157 aa)    
Predicted Functional Partners:
ptsO
Phosphocarrier protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri phosphocarrier protein PtsO or Npr or RpoR or b3206 or c3966 or z4569 or ecs4085 or sf3246 SWALL:PTSO_ECOLI (SWALL:P33996) (90 aa) fasta scores: E(): 5.4e-26, 83.33% id in 90 aa.
 
 
 0.992
fruA
Similar to Escherichia coli pts system, fructose-specific IIbc component FruA or PtsF or b2167 SWALL:PTFB_ECOLI (SWALL:P20966) (563 aa) fasta scores: E(): 1.4e-146, 75.13% id in 567 aa.
 
 
 0.948
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.920
ECA0287
Similar to Klebsiella pneumoniae probable sigma(54) modulation protein SWALL:RP5M_KLEPN (SWALL:P17161) (95 aa) fasta scores: E(): 7e-26, 76.84% id in 95 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri probable sigma (54) modulation protein Yhbh SWALL:RP5M_ECOLI (SWALL:P31221) (95 aa) fasta scores: E(): 2.4e-25, 77.89% id in 95 aa.
  
  
 0.833
rapZ
Putative P-loop ATPase family protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.
  
  
 0.801
mtlA
Similar to Escherichia coli PTS system, mannitol-specific IIabc component MtlA or b3599 SWALL:PTMA_ECOLI (SWALL:P00550) (637 aa) fasta scores: E(): 1.1e-188, 81.63% id in 637 aa.
  
 
 0.798
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.789
ptsP
Similar to Escherichia coli phosphoenolpyruvate-protein phosphotransferase PtsP or b2829 SWALL:PT1P_ECOLI (SWALL:P37177) (748 aa) fasta scores: E(): 1.6e-214, 74.02% id in 747 aa, and to Salmonella typhimurium phosphoenolpyruvate-protein phosphotransferase PtsP or stm3003 SWALL:PT1P_SALTY (SWALL:P37178) (748 aa) fasta scores: E(): 2.6e-215, 73.36% id in 747 aa; Belongs to the PEP-utilizing enzyme family.
  
   
 0.787
fruK
1-phosphofructokinase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 1-phosphofructokinase FruK or Fpk or b2168 or c2703 or z3426 or ecs3060 or sf2253 SWALL:K1PF_ECOLI (SWALL:P23539) (312 aa) fasta scores: E(): 7.8e-108, 90.7% id in 312 aa; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.782
ECA0342
PTS system, EIIa component; Similar to Escherichia coli O6 putative phosphotransferase system c4487 SWALL:AAN82923 (EMBL:AE016769) (156 aa) fasta scores: E(): 1.7e-44, 79.73% id in 153 aa, and to Listeria monocytogenes hypothetical protein Lmo2137 lmo2137 SWALL:Q8Y5C8 (EMBL:AL591982) (157 aa) fasta scores: E(): 2.2e-23, 48.99% id in 149 aa.
  
     0.766
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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