STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoNRNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa)    
Predicted Functional Partners:
ECA3255
Similar to Yersinia pestis two-component system response regulator ypo2914 SWALL:Q8ZCQ7 (EMBL:AJ414154) (445 aa) fasta scores: E(): 1.3e-149, 91.91% id in 445 aa, and to Salmonella typhimurium putative transcriptional regulator of two-component regulator protein yfha or stm2562 SWALL:Q8ZN32 (EMBL:AE008816) (445 aa) fasta scores: E(): 1.3e-142, 86.96% id in 445 aa.
 
  
 0.954
pspF
Similar to Escherichia coli psp operon transcriptional activator pspf or b1303 SWALL:PSPF_ECOLI (SWALL:P37344) (325 aa) fasta scores: E(): 1.8e-95, 76.61% id in 325 aa.
 
 
 
 0.946
ECA3257
Similar to Yersinia pestis two-component system sensor kinase ypo2916 or y1313 SWALL:Q8ZCQ5 (EMBL:AJ414154) (483 aa) fasta scores: E(): 5.4e-148, 79.91% id in 478 aa, and to Salmonella typhimurium putative sensory kinase in regulatory system yfhk or stm2564 SWALL:Q8ZN30 (EMBL:AE008816) (480 aa) fasta scores: E(): 6.7e-134, 73.67% id in 471 aa.
     
 0.903
rpoC
DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.887
rpoB
DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.881
ECA3435
Similar to Vibrio cholerae sigma-54 dependent transcriptional regulator vca0117 SWALL:Q9KN48 (EMBL:AE004353) (530 aa) fasta scores: E(): 9.9e-52, 40.46% id in 519 aa, and to Escherichia coli hypothetical sigma-54-dependent transcriptional regulator ygev or b2869 SWALL:YGEV_ECOLI (SWALL:Q46802) (592 aa) fasta scores: E(): 1.8e-39, 35.61% id in 438 aa.
 
   
 0.836
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.835
ptsN
Similar to Escherichia coli, and Shigella flexneri nitrogen regulatory IIA protein PtsN or RpoP SWALL:PTSN_ECOLI (SWALL:P31222) (163 aa) fasta scores: E(): 1.3e-46, 80.12% id in 156 aa, and to Yersinia pestis phosphotransferase system enzyme IIA PtsN SWALL:AAM83751 (EMBL:AE013615) (164 aa) fasta scores: E(): 6.1e-48, 81.01% id in 158 aa.
  
  
 0.833
ECA0287
Similar to Klebsiella pneumoniae probable sigma(54) modulation protein SWALL:RP5M_KLEPN (SWALL:P17161) (95 aa) fasta scores: E(): 7e-26, 76.84% id in 95 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri probable sigma (54) modulation protein Yhbh SWALL:RP5M_ECOLI (SWALL:P31221) (95 aa) fasta scores: E(): 2.4e-25, 77.89% id in 95 aa.
  
  
 0.817
hyfR
Similar to Escherichia coli hydrogenase-4 transcriptional activator HyfR or b2491 SWALL:HYFR_ECOLI (SWALL:P71229) (670 aa) fasta scores: E(): 2e-110, 50.07% id in 655 aa.
 
   
 0.815
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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