STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpoNRNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa)    
Predicted Functional Partners:
ECA3255
Similar to Yersinia pestis two-component system response regulator ypo2914 SWALL:Q8ZCQ7 (EMBL:AJ414154) (445 aa) fasta scores: E(): 1.3e-149, 91.91% id in 445 aa, and to Salmonella typhimurium putative transcriptional regulator of two-component regulator protein yfha or stm2562 SWALL:Q8ZN32 (EMBL:AE008816) (445 aa) fasta scores: E(): 1.3e-142, 86.96% id in 445 aa.
 
  
 0.987
ECA3257
Similar to Yersinia pestis two-component system sensor kinase ypo2916 or y1313 SWALL:Q8ZCQ5 (EMBL:AJ414154) (483 aa) fasta scores: E(): 5.4e-148, 79.91% id in 478 aa, and to Salmonella typhimurium putative sensory kinase in regulatory system yfhk or stm2564 SWALL:Q8ZN30 (EMBL:AE008816) (480 aa) fasta scores: E(): 6.7e-134, 73.67% id in 471 aa.
     
 0.945
ptsN
Similar to Escherichia coli, and Shigella flexneri nitrogen regulatory IIA protein PtsN or RpoP SWALL:PTSN_ECOLI (SWALL:P31222) (163 aa) fasta scores: E(): 1.3e-46, 80.12% id in 156 aa, and to Yersinia pestis phosphotransferase system enzyme IIA PtsN SWALL:AAM83751 (EMBL:AE013615) (164 aa) fasta scores: E(): 6.1e-48, 81.01% id in 158 aa.
  
  
 0.920
rpoB
DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.888
pspF
Similar to Escherichia coli psp operon transcriptional activator pspf or b1303 SWALL:PSPF_ECOLI (SWALL:P37344) (325 aa) fasta scores: E(): 1.8e-95, 76.61% id in 325 aa.
 
 
 
 0.883
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.881
ECA3435
Similar to Vibrio cholerae sigma-54 dependent transcriptional regulator vca0117 SWALL:Q9KN48 (EMBL:AE004353) (530 aa) fasta scores: E(): 9.9e-52, 40.46% id in 519 aa, and to Escherichia coli hypothetical sigma-54-dependent transcriptional regulator ygev or b2869 SWALL:YGEV_ECOLI (SWALL:Q46802) (592 aa) fasta scores: E(): 1.8e-39, 35.61% id in 438 aa.
 
  
 0.873
rpoZ
DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.869
glnG
Nitrogen regulation two-component system, response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 
  
 0.863
rpoS
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
   
 
 0.861
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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