STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
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[Homology]
Score
lptAPutative exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (190 aa)    
Predicted Functional Partners:
lptC
Putative exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
 
 0.999
ECA0289
ABC transporter, ATP-binding component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri probable ABC transporter ATP-binding protein YhbG SWALL:AAN44707 (EMBL:D12938) (241 aa) fasta scores: E(): 2.5e-76, 90.87% id in 241 aa, and to Salmonella typhimurium, and Salmonella typhi putative ABC superfamily Yhbg SWALL:Q8XFR6 (EMBL:AE008852) (241 aa) fasta scores: E(): 1.1e-75, 90.04% id in 241 aa.
  
  
 0.990
imp
Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
 
 0.931
ECA0292
Conserved hypothetical protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.
  
  
 0.878
ECA0293
Similar to Yersinia pestis hypothetical protein ypo3577 SWALL:Q8ZB48 (EMBL:AJ414157) (328 aa) fasta scores: E(): 2e-101, 81.59% id in 326 aa, and to Escherichia coli hypothetical protein Yrbh SWALL:YRBH_ECOLI (SWALL:P45395) (328 aa) fasta scores: E(): 2e-95, 78.08% id in 324 aa.
  
  
 0.854
ECA3269
HlyD family secretion protein; Similar to Rhizobium leguminosarum PrsE protein prsE SWALL:O05694 (EMBL:Y12758) (435 aa) fasta scores: E(): 4.6e-27, 29.72% id in 434 aa, and to Pseudomonas putida HlyD family secretion protein pp0166 SWALL:AAN65799 (EMBL:AE016774) (458 aa) fasta scores: E(): 1.9e-103, 65.19% id in 454 aa.
  
 
 0.771
ECA0294
Similar to Yersinia pestis putative sodium/calcium exchanger protein ypo3576 SWALL:Q8ZB49 (EMBL:AJ414157) (324 aa) fasta scores: E(): 1.8e-83, 71.69% id in 318 aa, and to Escherichia coli hypothetical protein YrbG SWALL:YRBG_ECOLI (SWALL:P45394) (325 aa) fasta scores: E(): 3.3e-71, 59.81% id in 321 aa.
     
 0.755
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.745
rlpB
Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.
  
  
 0.706
smpA
Putative outer membrane lipopotein (small protein A); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.674
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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